Houston vs TCU Prediction, Odds, Picks, Best Bets for Week 13 2025

Saturday's slate in college football includes a matchup between the Houston Cougars and the TCU Horned Frogs.

We've got you covered, in terms of the vital information about NCAA football betting lines, before you make your wager on FanDuel Sportsbook.

Houston vs TCU Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Houston: (-122) | TCU: (+104)
• Spread: Houston: -1.5 (-112) | TCU: +1.5 (-108)
• Total: 54.5 -- Over: (-115) | Under: (-105)

Houston vs TCU Betting Trends

• Houston's record against the spread is 7-3-0.
• Houston owns an ATS record of 5-2 as 1.5-point or greater favorites.
• This season, seven of Houston's 10 games have go over the point total.
• TCU has covered the spread four times in 10 games.
• TCU doesn't have a win ATS (0-2) as a 1.5-point underdog or more this season.
• This year, five of TCU's 10 games have gone over the point total.

Houston vs TCU Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Cougars win (54.7%)

Houston vs TCU Point Spread

Houston is favored by 1.5 points over TCU. Houston is -112 to cover the spread, with TCU being -108.

Houston vs TCU Over/Under

Houston versus TCU, on Nov. 22, has an over/under of 54.5, with the over being -115 and the under -105.

Houston vs TCU Moneyline

The moneyline numbers for Houston vs. TCU reveal Houston as the favorite (-122) and TCU as the underdog (+104).

Houston vs. TCU Points Insights

Houston vs. TCU Game Info

• Game day: Saturday, November 22, 2025
• Game time: 4 p.m. ET
• TV channel: FOX
• Location: Houston, Texas
• Stadium: TDECU Stadium

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Check out even more in-depth Houston vs. TCU analysis on FanDuel Research.