Houston vs Syracuse College Basketball Prediction, Odds, Picks, Best Bets for Nov. 24

Two hot teams meet when the Houston Cougars (5-0) visit the Syracuse Orange (4-0) on November 24, 2025. The Cougars will put their five-game win streak on the line against the Orange, winners of four straight.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Houston vs. Syracuse Game Info and Odds

• Game day: Monday, November 24, 2025
• Game time: 6 p.m. ET
• TV channel: TNT
• Location: Las Vegas, Nevada
• Arena: MGM Grand Garden Arena

To help you make an informed wager on Houston-Syracuse matchup (in which Houston is a 14.5-point favorite and the over/under has been set at 141.5 points), keep reading for some betting insights and trends for Monday's game.

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Houston vs. Syracuse: ATS Betting Stats and Trends

• Houston compiled a 22-17-0 record against the spread last season.
• Syracuse covered 17 times in 32 games with a spread last year.
• As a 14.5-point favorite or more in 2024-25, Houston was 9-4 against the spread compared to the 1-2 ATS record Syracuse put up as a 14.5-point underdog.
• The Cougars covered the spread in a lower percentage of their home games than away games last season. They covered 10 times in 17 games at home, and they covered seven times in 10 games on the road.
• The Orange were better against the spread at home (9-8-0) than on the road (5-6-0) last season.

Houston vs. Syracuse: Moneyline Betting Stats

• Houston won 88.9% of the games last season in which it was the moneyline favorite (32-4).
• The Cougars won all 13 games they played as a moneyline favorite with odds of -1587 or shorter.
• Syracuse was an underdog 21 times last season and won four, or 19%, of those games.
• Last season, the Orange were at least a +860 underdog on the moneyline three times, losing each of those contests.
• Based on this matchup's moneyline, Houston's implied win probability is 94.1%.

Houston vs. Syracuse Head-to-Head Comparison

• Houston was 182nd in college basketball in points scored (73.7 per game) and best in points conceded (58.7) last season.
• Houston was 96th in the country in rebounds per game (33.3) and 10th-best in rebounds allowed (26.9) last year.
• Houston was 292nd in college basketball in assists (12.0 per game) last season.
• In terms of turnovers, Houston was third-best in the nation in committing them (8.4 per game) last season. It was 85th in forcing them (12.3 per game).
• Syracuse put up 74.7 points per game (147th-ranked in college basketball) last year, while giving up 77.8 points per contest (322nd-ranked).
• Syracuse grabbed 33.6 boards per game (75th-ranked in college basketball). It gave up 31.1 rebounds per contest (172nd-ranked).
• Last season Syracuse ranked 174th in college basketball in assists, putting up 13.6 per game.
• Syracuse, who ranked 259th in college basketball with 12.0 turnovers per game, forced 9.5 turnovers per contest, which was 25th-worst in the country.

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