Hornets vs. Cavaliers Prediction, Odds, Picks, Best Bets for Jan. 21

Hornets vs. Cavaliers Game Info

• Date: Wednesday, January 21, 2026
• Time: 7 p.m. ET
• Venue: Spectrum Center -- Charlotte, North Carolina
• Coverage: ESPN, FDSSE, and FDSOH

The Charlotte Hornets (16-27) are slight underdogs (by 2.5 points) to break a four-game home losing streak when they host the Cleveland Cavaliers (24-20) on Wednesday, January 21, 2026 at 7 p.m. ET. The matchup has a point total of 236.5.

Hornets vs. Cavaliers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Hornets vs. Cavaliers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Cavaliers win (56.9%)

Hornets vs. Cavaliers Betting Trends

• The Cavaliers are 16-28-0 against the spread this season.
• The Hornets have played 43 games, with 25 wins against the spread.
• Cavaliers games have finished with a final combined score above the over/under 21 times out of 43 chances this season.
• Hornets games this year have hit the over 41.9% of the time (18 out of 43 games with a set point total).
• Cleveland owns a worse record against the spread when playing at home (8-17-0) than it does in away games (8-11-0).
• In terms of point totals, the Cavaliers hit the over less often in home games, as they've exceeded the total 10 times in 25 opportunities this season (40%). In away games, they have hit the over 11 times in 19 opportunities (57.9%).
• Charlotte has performed better against the spread away (14-10-0) than at home (11-8-0) this year.
• In 2025-26 a lower percentage of the Hornets' games have finished above the over/under at home (36.8%, seven of 19) than away (45.8%, 11 of 24).

Cavaliers Leaders

• Donovan Mitchell is averaging 29 points, 4.8 boards and 5.7 assists. At the other end, he averages 1.5 steals (eighth in NBA) and 0.3 blocked shots.
• Evan Mobley's numbers on the season are 17.8 points, 8.6 rebounds and 4.2 assists per game, shooting 51.7% from the floor and 32.6% from beyond the arc, with an average of 1.2 made treys.
• Jaylon Tyson is averaging 13.5 points, 2.1 assists and 5.4 boards.
• Jarrett Allen is averaging 13.5 points, 2.1 assists and 7.9 rebounds.
• De'Andre Hunter is averaging 14.1 points, 4.4 rebounds and 2.2 assists.

Hornets Leaders

• Per game, Miles Bridges gives the Hornets 19.1 points, 6.4 boards and 3.6 assists. He also averages 0.5 steals and 0.5 blocks.
• Kon Knueppel's numbers on the season are 19 points, 5.3 boards and 3.5 assists per contest. He is making 48.8% of his shots from the field and 43.5% from 3-point range, with an average of 3.4 triples (seventh in league).
• Per game, LaMelo Ball gives the Hornets 19.9 points, 5 boards and 7.6 assists, plus 1.2 steals and 0.2 blocks.
• Moussa Diabate's numbers on the season are 8.1 points, 8.4 rebounds and 1.5 assists per game. He is making 61.5% of his shots from the floor.
• Brandon Miller's numbers on the season are 19.8 points, 4.3 boards and 3.4 assists per contest. He is draining 41.7% of his shots from the floor and 36.2% from 3-point range, with an average of 2.9 treys.

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