Hornets vs. Cavaliers Prediction, Odds, Picks, Best Bets for Jan. 21

Hornets vs. Cavaliers Game Info

• Date: Wednesday, January 21, 2026
• Time: 7 p.m. ET
• Venue: Spectrum Center -- Charlotte, North Carolina
• Coverage: ESPN, FDSSE, and FDSOH

The Charlotte Hornets (16-27) are only 3-point underdogs as they attempt to stop a four-game home losing streak when they take on the Cleveland Cavaliers (24-20) on Wednesday, January 21, 2026 at Spectrum Center. The contest airs at 7 p.m. ET on ESPN, FDSSE, and FDSOH. The matchup has an over/under set at 237.5 points.

Hornets vs. Cavaliers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Hornets vs. Cavaliers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Cavaliers win (56.4%)

Hornets vs. Cavaliers Betting Trends

• The Cavaliers are 16-28-0 against the spread this season.
• The Hornets have 25 wins against the spread in 43 games this season.
• This season, 21 of the Cavaliers' games have gone over the point total out of 43 chances.
• Hornets games this season have gone over the point total 41.9% of the time (18 out of 43 games with a set point total).
• Cleveland sports a worse record against the spread in home games (8-17-0) than it does in road games (8-11-0).
• The Cavaliers have eclipsed the total less often when playing at home, hitting the over in 10 of 25 home matchups (40%). In road games, they have hit the over in 11 of 19 games (57.9%).
• In 2025-26 against the spread, Charlotte has a lower winning percentage at home (.579, 11-8-0 record) than on the road (.583, 14-10-0).
• Hornets games have gone above the over/under 36.8% of the time at home (seven of 19), and 45.8% of the time away (11 of 24).

Cavaliers Leaders

• Donovan Mitchell is averaging 29 points, 5.7 assists and 4.8 rebounds.
• Evan Mobley averages 17.8 points, 8.6 rebounds and 4.2 assists, shooting 51.7% from the field and 32.6% from downtown, with 1.2 made 3-pointers per game.
• Jaylon Tyson is averaging 13.5 points, 5.4 boards and 2.1 assists. At the other end, he averages 1 steal and 0.5 blocked shots.
• Jarrett Allen is averaging 13.5 points, 7.9 rebounds and 2.1 assists. Defensively, he averages 1 steal and 0.8 blocked shots.
• De'Andre Hunter is averaging 14.1 points, 4.4 boards and 2.2 assists. Defensively, he averages 0.6 steals and 0.2 blocked shots.

Hornets Leaders

• Per game, Miles Bridges provides the Hornets 19.1 points, 6.4 boards and 3.6 assists. He also averages 0.5 steals and 0.5 blocks.
• Kon Knueppel's numbers on the season are 19 points, 5.3 boards and 3.5 assists per contest. He is making 48.8% of his shots from the field and 43.5% from 3-point range, with an average of 3.4 treys (sixth in league).
• LaMelo Ball averages 19.9 points, 5 boards and 7.6 assists. He is sinking 41.4% of his shots from the field and 37% from beyond the arc, with 3.4 treys per contest (sixth in league).
• Moussa Diabate's numbers on the season are 8.1 points, 8.4 boards and 1.5 assists per contest. He is sinking 61.5% of his shots from the field.
• The Hornets are receiving 19.8 points, 4.3 rebounds and 3.4 assists per game from Brandon Miller.

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