Celtics vs. Pacers Prediction, Odds, Picks, Best Bets for Jan. 21

Celtics vs. Pacers Game Info

• Date: Wednesday, January 21, 2026
• Time: 7:30 p.m. ET
• Venue: TD Garden -- Boston, Massachusetts
• Coverage: FDSIN, NBCS-BOS, and WTHR-13

The Boston Celtics (26-16) are heavy, 11-point favorites against the Indiana Pacers (10-34) on Wednesday, January 21, 2026 at 7:30 p.m. ET. The matchup airs on FDSIN, NBCS-BOS, and WTHR-13. The over/under is set at 227.5 in the matchup.

Celtics vs. Pacers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Celtics vs. Pacers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Celtics win (83.2%)

Celtics vs. Pacers Betting Trends

• The Celtics are 24-17-1 against the spread this season.
• In the Pacers' 44 games this year, they have 22 wins against the spread.
• This season, 18 of the Celtics' games have gone over the point total out of 44 chances.
• Pacers games this season have gone over the point total 36.4% of the time (16 out of 44 games with a set point total).
• Against the spread, Boston has performed worse at home, covering nine times in 19 home games, and 15 times in 23 road games.
• The Celtics have hit the over on the over/under in nine of 19 home games (47.4%), compared to nine of 23 road games (39.1%).
• In 2025-26 against the spread, Indiana has a better winning percentage at home (.583, 14-10-0 record) than on the road (.400, 8-12-0).
• In 2025-26, a higher percentage of the Pacers' games have finished above the over/under at home (41.7%, 10 of 24) compared to on the road (30%, six of 20).

Celtics Leaders

• Jaylen Brown averages 29.8 points, 6.6 rebounds and 4.7 assists.
• Derrick White averages 17.7 points, 4.6 rebounds and 5.4 assists, shooting 39.1% from the field and 32.4% from downtown, with 3 made treys per game.
• Payton Pritchard averages 16.6 points, 4.4 boards and 5.3 assists.
• Neemias Queta is averaging 10.2 points, 1.4 assists and 8.2 rebounds.
• Anfernee Simons' numbers on the season are 14 points, 2.4 boards and 2.5 assists per game, shooting 44% from the field and 40.2% from beyond the arc, with an average of 2.6 made 3-pointers.

Pacers Leaders

• Pascal Siakam averages 23.6 points for the Pacers, plus 6.9 rebounds and 4 assists.
• Andrew Nembhard's numbers on the season are 17.6 points, 2.6 rebounds and 7.1 assists per contest. He is sinking 44.9% of his shots from the floor and 36.6% from beyond the arc, with an average of 1.9 treys.
• Per game, Jay Huff gets the Pacers 8.8 points, 3.8 boards and 1.3 assists, plus 0.4 steals and 2.1 blocks (second in NBA).
• Per game, Jarace Walker provides the Pacers 9 points, 4.3 rebounds and 1.9 assists, plus 0.6 steals and 0.4 blocks.
• Per game, T.J. McConnell gets the Pacers 9.9 points, 2.2 rebounds and 5 assists, plus 1.2 steals and 0.2 blocks.

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