Celtics vs. Pacers Prediction, Odds, Picks, Best Bets for Jan. 21

Celtics vs. Pacers Game Info

• Date: Wednesday, January 21, 2026
• Time: 7:30 p.m. ET
• Venue: TD Garden -- Boston, Massachusetts
• Coverage: FDSIN, NBCS-BOS, and WTHR-13

The Boston Celtics (26-16) take on the Indiana Pacers (10-34) as heavy, 11-point favorites on Wednesday, January 21, 2026 at 7:30 p.m. ET on FDSIN, NBCS-BOS, and WTHR-13. The over/under is 226.5 for the matchup.

Celtics vs. Pacers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Celtics vs. Pacers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Celtics win (84%)

Celtics vs. Pacers Betting Trends

• The Celtics have covered the spread 24 times this season (24-17-1).
• The Pacers have 22 wins against the spread in 44 games this year.
• Celtics games have finished with a final combined score above the over/under 18 times out of 44 chances this season.
• Pacers games this year have gone over the point total 36.4% of the time (16 out of 44 games with a set point total).
• At home, Boston owns a worse record against the spread (9-10-0) compared to its ATS record on the road (15-7-1).
• The Celtics have hit the over on the total in a higher percentage of games at home (47.4%) than road games (39.1%).
• Indiana has performed better against the spread at home (14-10-0) than on the road (8-12-0) this year.
• Pacers games have finished above the over/under more frequently at home (10 times out of 24) than on the road (six of 20) this year.

Celtics Leaders

• Jaylen Brown averages 29.8 points, 6.6 rebounds and 4.7 assists.
• Derrick White averages 17.7 points, 4.6 rebounds and 5.4 assists.
• Payton Pritchard averages 16.6 points, 4.4 rebounds and 5.3 assists, shooting 45% from the field and 33.9% from beyond the arc, with 2.5 made treys per contest.
• Neemias Queta is averaging 10.2 points, 1.4 assists and 8.2 boards.
• Anfernee Simons is averaging 14 points, 2.4 boards and 2.5 assists. Defensively, he averages 0.5 steals and 0.1 blocked shots.

Pacers Leaders

• Per game, Pascal Siakam gets the Pacers 23.6 points, 6.9 boards and 4 assists. He also averages 1.2 steals and 0.4 blocks.
• The Pacers are getting 17.6 points, 2.6 rebounds and 7.1 assists per game from Andrew Nembhard.
• The Pacers are receiving 8.8 points, 3.8 boards and 1.3 assists per game from Jay Huff.
• Per game, Jarace Walker provides the Pacers 9 points, 4.3 rebounds and 1.9 assists, plus 0.6 steals and 0.4 blocks.
• Per game, T.J. McConnell gives the Pacers 9.9 points, 2.2 boards and 5 assists, plus 1.2 steals and 0.2 blocks.

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