Heat vs. Grizzlies Prediction, Odds, Picks, Best Bets for Feb. 21

Heat vs. Grizzlies Game Info

• Date: Saturday, February 21, 2026
• Time: 8 p.m. ET
• Venue: Kaseya Center -- Miami, Florida
• Coverage: FDSSUN, FDSSE, and WPLG

The Memphis Grizzlies (21-33) are heavy underdogs (-10) as they look to stop a four-game road slide when they visit the Miami Heat (30-27) on Saturday, February 21, 2026 at Kaseya Center. The matchup airs at 8 p.m. ET on FDSSUN, FDSSE, and WPLG. The point total is 238.5 for the matchup.

Heat vs. Grizzlies Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Heat vs. Grizzlies Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Heat win (69.1%)

Heat vs. Grizzlies Betting Trends

• The Heat have covered the spread 33 times over 57 games with a set spread.
• The Grizzlies have 25 wins against the spread in 54 games this season.
• Heat games have finished with a final combined score above the over/under 29 times out of 54 chances this season.
• The Grizzlies have eclipsed the over/under 46.3% of the time this year (25 of 54 games with a set point total).
• Miami has done a better job covering the spread in road games (19-10-1) than it has in home games (14-13-0).
• The Heat have exceeded the total in 14 of 27 home games (51.9%), compared to 15 of 30 road games (50%).
• Memphis' winning percentage against the spread at home is .444 (12-15-0). Away, it is .481 (13-13-1).
• In 2025-26, a higher percentage of the Grizzlies' games have finished above the over/under at home (51.9%, 14 of 27) compared to on the road (40.7%, 11 of 27).

Heat Leaders

• Bam Adebayo's numbers on the season are 18.4 points, 9.9 rebounds and 2.8 assists per contest, shooting 44.5% from the floor and 33.6% from beyond the arc, with an average of 1.6 made treys.
• Jaime Jaquez Jr. averages 15.1 points, 5.4 boards and 4.7 assists.
• Norman Powell is averaging 22.8 points, 2.6 assists and 3.6 rebounds.
• Andrew Wiggins is averaging 15.9 points, 2.7 assists and 5 rebounds.
• Kel'el Ware is averaging 11.4 points, 9.3 rebounds and 0.6 assists.

Grizzlies Leaders

• Cam Spencer averages 11.6 points, 2.7 rebounds and 5.7 assists. He is also draining 47.8% of his shots from the field and 44.8% from 3-point range (seventh in NBA), with 2.1 triples per game.
• The Grizzlies get 13.3 points per game from Cedric Coward, plus 6.2 boards and 2.9 assists.
• Santi Aldama averages 14 points, 6.7 rebounds and 2.9 assists. He is sinking 47.9% of his shots from the floor and 35% from 3-point range, with 1.6 triples per game.
• Jaylen Wells' numbers on the season are 12.1 points, 3.4 boards and 1.7 assists per game. He is making 41.2% of his shots from the field and 33.8% from 3-point range, with an average of 1.8 triples.
• Per game, Walter Clayton Jr. gets the Grizzlies 6.9 points, 2 rebounds and 3.3 assists, plus 0.6 steals and 0.3 blocks.

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