Guardians vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 18

Odds updated as of 2:12 a.m.

On Tuesday in MLB, the Cleveland Guardians are up against the San Francisco Giants.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important information about this matchup.

Guardians vs Giants Game Info

• Cleveland Guardians (60-65) vs. San Francisco Giants (51-73)
• Date: Tuesday, August 18, 2026
• Time: 6:40 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: CleGuardians.TV and NBCS-BA

Guardians vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-190) | SF: (+160)
• Spread: CLE: -1.5 (+114) | SF: +1.5 (-137)
• Total: 8 -- Over: (-115) | Under: (-105)

Guardians vs Giants Probable Starting Pitchers

Probable Pitchers: Foster Griffin (Guardians) - 13-4, 3.25 ERA vs Carson Whisenhunt (Giants) - 3-3, 6.11 ERA

The Guardians will give the nod to Foster Griffin (13-4, 3.25 ERA), who is eyeing win No. 14 on the season, and the Giants will turn to Carson Whisenhunt (3-3, 6.11 ERA). When Griffin starts, his team is 15-8-0 against the spread this season. Griffin's team has a record of 5-1 this season when he starts and they are the favorite on the moneyline. The Giants have a 4-2-0 ATS record in Whisenhunt's six starts that had a set spread. The Giants have a 2-3 record in Whisenhunt's five starts this season when they were the moneyline underdog.

Guardians vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Guardians win (57.2%)

Guardians vs Giants Moneyline

• San Francisco is the underdog, +160 on the moneyline, while Cleveland is a -190 favorite at home.

Guardians vs Giants Spread

• The Guardians are hosting the Giants and are favored by 1.5 runs (+114 to cover) on the runline. San Francisco is -137 to cover.

Guardians vs Giants Over/Under

• The Guardians-Giants contest on Aug. 18 has been given an over/under of 8 runs. The over is set at -115 and the under at -105.

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Guardians vs Giants Betting Trends

• The Guardians have been favorites in 67 games this season and have come away with the win 31 times (46.3%) in those contests.
• Cleveland has not played a game this season with better moneyline odds than -190.
• The Guardians and their opponents have gone over in 58 of their 119 games with a total set by sportsbooks this season.
• The Guardians have an against the spread record of 56-63-0 in 119 games with a line this season.
• The Giants have won 35.1% of the games this season they were the moneyline underdog (27-50).
• San Francisco is 3-4 (winning 42.9% of its games) when playing as a moneyline underdog of +160 or longer.
• In the 121 games oddsmakers have set an over/under for the Giants, they have combined with opponents to go over the total 56 times (56-56-9).
• The Giants have a 55-66-0 record against the spread this season.

Guardians Player Leaders

• Chase DeLauter leads Cleveland in slugging percentage (.442) and total hits (115) this season. He's batting .285 with an on-base percentage of .358.
• He is 20th in batting average, 37th in on-base percentage, and 56th in slugging among qualifying hitters in MLB.
• Jose Ramirez is hitting .236 with 19 doubles, 10 home runs and 54 walks, while slugging .382 with an on-base percentage of .341.
• Among qualified hitters, he ranks 107th in batting average, 59th in on-base percentage and 114th in slugging percentage.
• Ramirez has picked up a hit in two games in a row. In his last five games he is hitting .200 with a double, five walks and two RBIs.
• Brayan Rocchio is batting .253 with a .376 slugging percentage and 51 RBI this year.
• Steven Kwan leads Cleveland with an OBP of .366 this season while batting .266 with 61 walks and 54 runs scored.

Giants Player Leaders

• Jung Hoo Lee has put up a .328 on-base percentage and a .432 slugging percentage, both team-high numbers for the Giants. He's batting .292.
• He is 12th in batting average, 78th in on-base percentage and 62nd in slugging percentage among all qualifying hitters in the big leagues.
• Rafael Devers is hitting .246 with 30 doubles, a triple, 25 home runs and 52 walks. He's slugging .474 with an on-base percentage of .320.
• Including all qualified hitters, he is 90th in batting average, 92nd in on-base percentage and 31st in slugging percentage.
• Willy Adames is batting .224 with 25 doubles, a triple, 19 home runs and 36 walks.
• Bryce Eldridge is hitting .247 with 15 doubles, 13 home runs and 42 walks.

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