Giants vs Orioles Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 29

Odds updated as of 9:12 a.m.

In MLB action on Friday, the San Francisco Giants face the Baltimore Orioles.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important info regarding this matchup.

Giants vs Orioles Game Info

• San Francisco Giants (66-68) vs. Baltimore Orioles (60-74)
• Date: Friday, August 29, 2025
• Time: 10:15 p.m. ET
• Venue: Oracle Park -- San Francisco, California
• Coverage: Apple TV+

Giants vs Orioles Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-158) | BAL: (+134)
• Spread: SF: -1.5 (+140) | BAL: +1.5 (-170)
• Total: 7.5 -- Over: (-106) | Under: (-114)

Giants vs Orioles Probable Starting Pitchers

Probable Pitchers: Robbie Ray (Giants) - 10-6, 2.93 ERA vs Dean Kremer (Orioles) - 9-9, 4.19 ERA

The Giants will call on Robbie Ray (10-6) versus the Orioles and Dean Kremer (9-9). Ray and his team are 16-10-0 ATS this season when he starts. Ray's team has won 70.6% of his starts when they are favored on the moneyline (12-5). The Orioles have a 13-12-0 ATS record in Kremer's 25 starts with a set spread. The Orioles have been the moneyline underdog in 13 of Kremer's starts this season, and they went 5-8 in those games.

Giants vs Orioles Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (56.2%)

Giants vs Orioles Moneyline

• Baltimore is a +134 underdog on the moneyline, while San Francisco is a -158 favorite at home.

Giants vs Orioles Spread

• The Giants are favored by 1.5 runs at home versus the Orioles. The Giants are +140 to cover the spread, while the Orioles are -170.

Giants vs Orioles Over/Under

• Giants versus Orioles on Aug. 29 has an over/under of 7.5 runs, with the odds on the over -106 and the under set at -114.

Bet on San Francisco Giants vs. Baltimore Orioles on FanDuel today!

Giants vs Orioles Betting Trends

• The Giants have been favorites in 79 games this season and have come away with the win 40 times (50.6%) in those contests.
• This season San Francisco has been victorious 14 times in 29 chances when named as a favorite of at least -158 on the moneyline.
• The Giants' games have gone over the total in 61 of their 133 opportunities.
• The Giants are 59-74-0 against the spread in their 133 games that had a posted line this season.
• The Orioles have won 32 of the 72 games they were the moneyline underdog this season (44.4%).
• Baltimore has a 5-12 record (winning only 29.4% of its games) when it has played as a moneyline underdog of +134 or longer.
• The Orioles have played in 131 games with a set over/under, and have combined with their opponents to go over the total 56 times (56-71-4).
• The Orioles have covered 47.3% of their games this season, going 62-69-0 against the spread.

Giants Player Leaders

• Rafael Devers leads San Francisco in OBP (.378) and total hits (129) this season. He's batting .258 batting average while slugging .478.
• Among all qualified hitters in MLB, his batting average ranks 78th, his on-base percentage ranks ninth, and he is 35th in slugging.
• Devers will look for his fourth straight game with a hit in this matchup. During his last five outings he is hitting .438 with a double, two home runs, three walks and six RBIs.
• Jung Hoo Lee is hitting .261 with 30 doubles, 10 triples, seven home runs and 41 walks. He's slugging .409 with an on-base percentage of .323.
• He is 70th in batting average, 88th in on-base percentage and 97th in slugging in MLB.
• Lee heads into this matchup looking to extend his four-game hit streak. In his last five games he is batting .238 with a double, a walk and an RBI.
• Willy Adames has 110 hits this season and has a slash line of .224/.313/.415.
• Heliot Ramos has an OPS of .746, fueled by an OBP of .339 and a team-best slugging percentage of .408 this season.

Orioles Player Leaders

• Gunnar Henderson has accumulated 132 hits with a .348 on-base percentage and a .461 slugging percentage, all club-highs for the Orioles. He's batting .277.
• Including all the qualified hitters in the big leagues, his batting average places him 33rd, his on-base percentage is 43rd, and he is 49th in slugging.
• Jackson Holliday is hitting .242 with 18 doubles, two triples, 15 home runs and 38 walks. He's slugging .377 with an on-base percentage of .303.
• His batting average ranks 114th among all qualified players, his on-base percentage is 126th, and he is 132nd in slugging.
• Colton Cowser is batting .219 with 11 doubles, 12 home runs and 17 walks.
• Ryan Mountcastle is hitting .251 with 14 doubles, four home runs and 11 walks.

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