Florida International vs Buffalo Prediction, Odds, Picks, Best Bets for Week 2 2026

On Saturday in college football, the Florida International Panthers are playing the Buffalo Bulls.

We've got you covered, in terms of the most important information about NCAA football betting lines, before you make your wager on FanDuel Sportsbook.

Florida International vs Buffalo Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Florida International: (-450) | Buffalo: (+340)
• Spread: Florida International: -10.5 (-106) | Buffalo: +10.5 (-114)
• Total: 47.5 -- Over: (-110) | Under: (-110)

Florida International vs Buffalo Betting Trends

• Florida International has covered the spread in every game this season.
• Buffalo is winless against the spread this season.
• Buffalo and its opponent have yet to hit the over this year.

Florida International vs Buffalo Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Panthers win (68.1%)

Florida International vs Buffalo Point Spread

Buffalo is a 10.5-point underdog against Florida International. Buffalo is -114 to cover the spread, and Florida International is -106.

Florida International vs Buffalo Over/Under

An over/under of 47.5 has been set for Florida International-Buffalo on Sept. 12, with the over being -110 and the under -110.

Florida International vs Buffalo Moneyline

Looking at the moneyline for Florida International-Buffalo, Florida International is the favorite at -450, and Buffalo is +340.

Florida International vs. Buffalo Points Insights

• The Panthers had an average implied point total of 31.8 last season, which is 2.8 points higher than their implied total in Saturday's game (29).
• The average implied point total last season for the Bulls (29.0) is 10.0 more points than the team's implied total in this matchup (19).

Florida International vs. Buffalo Game Info

• Game day: Saturday, September 12, 2026
• Game time: 6 p.m. ET
• TV channel: ESPN+
• Location: Miami, Florida
• Stadium: Pitbull Stadium

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Check out even more in-depth Florida International vs. Buffalo analysis on FanDuel Research.