Duke vs SMU College Basketball Prediction, Odds, Picks, Best Bets for Jan. 10

The Duke Blue Devils (14-1, 3-0 ACC) hope to continue a three-game win streak when they host the SMU Mustangs (12-3, 1-1 ACC) on January 10, 2026 at Cameron Indoor Stadium.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Duke vs. SMU Game Info and Odds

• Game day: Saturday, January 10, 2026
• Game time: 2 p.m. ET
• TV channel: ESPN
• Location: Durham, North Carolina
• Arena: Cameron Indoor Stadium

Before placing a wager on Saturday's Duke-SMU spread (Duke -14.5) or over/under (157.5 points), check out the betting trends and insights below.

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Duke vs. SMU: ATS Betting Stats and Trends

• Duke is 7-8-0 ATS this season.
• SMU has won seven games against the spread this season, while failing to cover eight times.
• The Blue Devils have a worse record against the spread in home games (2-5-0) than they do in away games (3-1-0).
• The Mustangs were better against the spread away (5-6-0) than at home (7-10-0) last season.

Duke vs. SMU: Moneyline Betting Stats

• Duke has been the moneyline favorite in nine games this season and has come away with the win eight times (88.9%) in those contests.
• The Blue Devils have been listed as a favorite of -1695 or more on two occasions this season and won both games.
• SMU has gone 2-3 in games it was the underdog on the moneyline (winning 40% of those games).
• The Mustangs have not played a game this season with moneyline odds of +890 or longer.
• Duke has an implied victory probability of 94.4% according to the moneyline set for this matchup.

Duke vs. SMU Head-to-Head Comparison

• Duke was the 11th-best team in college basketball in points scored (83.2 per game) and seventh-best in points allowed (62.8) last season.
• Duke was the 24th-best team in college basketball in rebounds per game (35.6) and 12th-best in rebounds allowed (27.3) last season.
• Last season Duke was 17th-best in college basketball in assists with 16.9 per game.
• Last season, Duke was ninth-best in the nation in turnovers committed (8.9 per game) and ranked 265th in turnovers forced (10.4).
• Offensively, SMU posted 79.9 points per game (40th-ranked in college basketball) last year. It ceded 71.3 points per contest at the other end (152nd-ranked).
• SMU grabbed 34.7 boards per game (43rd-ranked in college basketball) last season, while allowing 29 rebounds per contest (53rd-ranked).
• SMU averaged 15.9 dimes per game, which ranked them 42nd in college basketball.
• SMU averaged 11.5 turnovers per game (221st-ranked in college basketball) this year, while forcing 12 turnovers per contest (112th-ranked).

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