Cubs vs Pirates Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 13

Odds updated as of 10:13 p.m.

MLB action on Sunday includes the Chicago Cubs playing the Pittsburgh Pirates.

We've got you covered, in terms of the vital info regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Cubs vs Pirates Game Info

• Chicago Cubs (83-66) vs. Pittsburgh Pirates (74-75)
• Date: Sunday, September 13, 2026
• Time: 2:20 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MARQ and SportsNet PT

Cubs vs Pirates Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-144) | PIT: (+122)
• Spread: CHC: -1.5 (+168) | PIT: +1.5 (-205)
• Total: 6.5 -- Over: (-110) | Under: (-110)

Cubs vs Pirates Probable Starting Pitchers

Probable Pitchers: Matthew Boyd (Cubs) - 8-4, 4.03 ERA vs Bubba Chandler (Pirates) - 7-9, 4.25 ERA

The Cubs will call on Matthew Boyd (8-4) against the Pirates and Bubba Chandler (7-9). Boyd and his team are 9-9-0 ATS this season when he starts. Boyd's team has won 66.7% of his starts when they are favored on the moneyline (8-4). The Pirates are 15-12-0 ATS in Chandler's 27 starts that had a set spread. The Pirates have been the moneyline underdog in 17 of Chandler's starts this season, and they went 7-10 in those games.

Cubs vs Pirates Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (56.2%)

Cubs vs Pirates Moneyline

• Chicago is the favorite, -144 on the moneyline, while Pittsburgh is a +122 underdog on the road.

Cubs vs Pirates Spread

• The Pirates are +1.5 on the run line against the Cubs. The Pirates are -205 to cover, and the Cubs are +168.

Cubs vs Pirates Over/Under

• Cubs versus Pirates, on Sept. 13, has an over/under of 6.5, with the over being -110 and the under -110.

Bet on Chicago Cubs vs. Pittsburgh Pirates on FanDuel today!

Cubs vs Pirates Betting Trends

• The Cubs have won in 55, or 57.3%, of the 96 contests they have been named as odds-on favorites in this year.
• This year Chicago has won 30 of 49 games when listed as at least -144 on the moneyline.
• The Cubs and their opponents have gone over in 80 of their 144 games with a total set by sportsbooks this season.
• The Cubs are 69-75-0 against the spread in their 144 games that had a posted line this season.
• The Pirates have compiled a 30-39 record in games they were listed as the moneyline underdog (winning 43.5% of those games).
• Pittsburgh has a record of 8-15 in games it has played as a moneyline underdog with odds of +122 or longer (34.8%).
• The Pirates have had an over/under set by bookmakers 147 times, and have combined with opponents to go over the total in 76 of those games (76-67-4).
• The Pirates are 71-76-0 ATS this season.

Cubs Player Leaders

• Pete Crow-Armstrong leads Chicago with 160 hits and an OBP of .373, plus a team-best slugging percentage of .566. He's batting .279.
• Among all qualifying hitters in baseball, he is 25th in batting average, 10th in on-base percentage, and second in slugging.
• Alex Bregman has 30 doubles, a triple, 25 home runs and 71 walks. He's batting .264 and slugging .450 with an on-base percentage of .353.
• He is 54th in batting average, 40th in on-base percentage and 47th in slugging in MLB.
• Bregman enters this matchup looking to extend his three-game hit streak. In his last five games he is hitting .412 with two doubles, a home run, two walks and three RBIs.
• Seiya Suzuki is batting .270 with a .480 slugging percentage and 81 RBI this year.
• Nico Hoerner is batting .267 with a .320 OBP and 67 RBI for Chicago this season.
• Hoerner brings a four-game hitting streak into this matchup. In his last five games he is batting .286 with a double and three RBIs.

Pirates Player Leaders

• Bryan Reynolds has put up an on-base percentage of .368, a team-high for the Pirates. He's batting .264 and slugging .429.
• Including all the qualifying hitters in the majors, his batting average puts him 54th, his on-base percentage is 17th, and he is 65th in slugging.
• Brandon Lowe has racked up 139 hits to lead his team. He has a batting average of .257 while slugging .474 with an on-base percentage of .327.
• He ranks 67th in batting average, 70th in on-base percentage and 28th in slugging percentage in the big leagues.
• Nick Gonzales has racked up an on-base percentage of .368 and a slugging percentage of .392. Both lead the Pirates.
• Ryan O'Hearn is hitting .268 with 15 doubles, 18 home runs and 31 walks.

Cubs vs Pirates Head to Head

• 9/12/2026: 4-3 CHC (Favorite: Cubs, Spread: -1.5, Total: 9.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 9/11/2026: 12-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 7/26/2026: 8-7 PIT (Favorite: Pirates, Spread: -1.5, Total: 9, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/25/2026: 11-0 CHC (Favorite: Pirates, Spread: -1.5, Total: 8, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 7/24/2026: 3-2 CHC (Favorite: Pirates, Spread: -1.5, Total: 8, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 5/28/2026: 7-2 CHC (Favorite: Pirates, Spread: -1.5, Total: 7.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 5/27/2026: 10-4 CHC (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 5/26/2026: 12-1 PIT (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 5/25/2026: 2-1 PIT (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 4/12/2026: 7-6 CHC (Favorite: Cubs, Spread: -1.5, Total: 12.5, Favorite Moneyline: -134, Underdog Moneyline: +116)

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