Chiefs vs Colts Prediction, Odds, Picks, Best Bets for NFL Week 2

NFL action on Sunday includes the Kansas City Chiefs facing the Indianapolis Colts.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NFL moneyline insights you need to know.

Chiefs vs Colts Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction: Chiefs win (58.6%)

Chiefs vs Colts Point Spread

The Chiefs are 6.5-point favorites against the Colts. The Chiefs are -102 to cover the spread, while the Colts are -120 to cover as a 6.5-point underdog.

Chiefs vs Colts Over/Under

The over/under for Chiefs-Colts on Sept. 20 is 45.5. The over is -115, and the under is -105.

Chiefs vs Colts Moneyline

The moneyline numbers for Chiefs vs. Colts reveal Kansas City as the favorite (-290) and Indianapolis as the underdog (+235) on the road.

Chiefs vs Colts Betting Trends

• The Chiefs were 6-11-0 against the spread last year.
• The Chiefs did not lose ATS (2-0) as a 6.5-point favorite or more last season.
• In 17 Kansas City games last year, four went over the total.
• The Colts' record against the spread last year was 9-8-0.
• Indianapolis went unbeaten ATS (2-0) as underdogs of 6.5 points or greater last season.
• Last season, nine of the Colts' 17 games hit the over.

Check out even more in-depth Chiefs vs. Colts analysis on FanDuel Research.

Chiefs vs Colts Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: KC: (-290) | IND: (+235)
• Spread: KC: -6.5 (-102) | IND: +6.5 (-120)
• Total: 45.5 -- Over: (-115) | Under: (-105)

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