Chiefs vs Colts Prediction, Odds, Picks, Best Bets for NFL Week 12

The NFL's Sunday schedule includes the Kansas City Chiefs taking on the Indianapolis Colts.

Before you place your bet on this game at FanDuel Sportsbook, here are the NFL moneyline insights you need to know.

Chiefs vs Colts Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction: Chiefs win (63.5%)

Chiefs vs Colts Point Spread

The Chiefs are 3.5-point favorites against the Colts. The Chiefs are -102 to cover the spread, while the Colts are -120 to cover as a 3.5-point underdog.

Chiefs vs Colts Over/Under

A total of 49.5 points has been set for the Chiefs-Colts game on Nov. 23, with the over available at -115 and the under at -105.

Chiefs vs Colts Moneyline

Looking at the moneyline for Chiefs-Colts, Kansas City is the favorite at -180, and Indianapolis is +152 playing on the road.

Chiefs vs Colts Betting Trends

• Kansas City is 5-5-0 against the spread this year.
• The Chiefs are 3-2 as 3.5-point favorites or more.
• There have been three Chiefs games (out of 10) that went over the total this season.
• The Colts' record against the spread is 6-4-0.
• Indianapolis is winless ATS (0-1) when playing as at least 3.5-point underdogs this season.
• This season, six of the Colts' 10 games have gone over the point total.

Check out even more in-depth Chiefs vs. Colts analysis on FanDuel Research.

Chiefs vs Colts Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: KC: (-180) | IND: (+152)
• Spread: KC: -3.5 (-102) | IND: +3.5 (-120)
• Total: 49.5 -- Over: (-115) | Under: (-105)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!