Chiefs vs Colts Prediction, Odds, Picks, Best Bets for NFL Week 12

Sunday's slate in the NFL includes a matchup between the Kansas City Chiefs and the Indianapolis Colts.

Get the latest NFL odds ahead of this matchup on FanDuel Sportsbook.

Chiefs vs Colts Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction: Chiefs win (63.5%)

Chiefs vs Colts Point Spread

The Chiefs are 3.5-point favorites against the Colts. The Chiefs are -108 to cover the spread, while the Colts are -112 to cover as a 3.5-point underdog.

Chiefs vs Colts Over/Under

An over/under of 49.5 has been set for Chiefs-Colts on Nov. 23, with the over being -115 and the under -105.

Chiefs vs Colts Moneyline

Indianapolis is a +158 underdog on the moneyline, while Kansas City is a -188 favorite on the road.

Chiefs vs Colts Betting Trends

• Kansas City's record against the spread is 5-5-0.
• The Chiefs' ATS record as 3.5-point favorites or more is 3-2.
• This year, three of the Chiefs' 10 games have hit the over.
• Against the spread, the Colts are 6-4-0 this year.
• Indianapolis has no wins ATS (0-1) as a 3.5-point underdog or greater this season.
• There have been six Colts games (out of 10) that went over the total this season.

Check out even more in-depth Chiefs vs. Colts analysis on FanDuel Research.

Chiefs vs Colts Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: KC: (-188) | IND: (+158)
• Spread: KC: -3.5 (-108) | IND: +3.5 (-112)
• Total: 49.5 -- Over: (-115) | Under: (-105)

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