Celtics vs. Nets Prediction, Odds, Picks, Best Bets for Nov. 21

Celtics vs. Nets Game Info

• Date: Friday, November 21, 2025
• Time: 7:30 p.m. ET
• Venue: TD Garden -- Boston, Massachusetts
• Coverage: NBCS-BOS and YES

The Boston Celtics (8-7) are heavy, 15.5-point favorites as they look to continue a three-game winning streak when they host the Brooklyn Nets (2-12) on Friday, November 21, 2025 at TD Garden. The game airs at 7:30 p.m. ET on NBCS-BOS and YES. The point total is set at 222.5 for the matchup.

Celtics vs. Nets Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Celtics vs. Nets Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Celtics win (86%)

Celtics vs. Nets Betting Trends

• The Celtics have put together a record of 6-8-1 against the spread this season.
• The Nets are 5-8-1 against the spread this year.
• Games involving the Celtics have hit the over six times out of 14 chances this season.
• Nets games this season have gone over the point total eight times in 14 opportunities (57.1%).
• When playing at home, Boston owns a better record against the spread (3-4-0) compared to its ATS record on the road (3-4-1).
• When it comes to point totals, the Celtics hit the over more often at home, as they've eclipsed the total four times in seven opportunities this season (57.1%). On the road, they have hit the over two times in eight opportunities (25%).
• In 2025-26 against the spread, Brooklyn has a lower winning percentage at home (.286, 2-5-0 record) than away (.429, 3-3-1).
• Nets games have gone above the over/under 57.1% of the time both at home (four of seven) and away (four of seven) this season.

Celtics Leaders

• Jaylen Brown is averaging 27.5 points, 5.5 boards and 4.1 assists. Defensively, he averages 0.8 steals and 0.3 blocked shots.
• Derrick White is averaging 15.9 points, 5.3 assists and 4 boards.
• Payton Pritchard averages 16.7 points, 4.3 boards and 5 assists.
• Neemias Queta is averaging 9.1 points, 8.1 boards and 1.7 assists.
• Anfernee Simons is averaging 13.3 points, 2.2 rebounds and 2.5 assists.

Nets Leaders

• Per game, Michael Porter Jr. gives the Nets 24.2 points, 7.7 boards and 3.2 assists. He also averages 0.8 steals and 0.2 blocks.
• Nic Claxton averages 14.6 points, 7.3 boards and 3.9 assists. He is also sinking 57.6% of his shots from the field.
• The Nets receive 9.4 points per game from Terance Mann, plus 3.1 boards and 3.4 assists.
• Noah Clowney averages 9.7 points, 3.7 rebounds and 1.6 assists. He is making 35.8% of his shots from the floor and 32.1% from beyond the arc, with 1.8 triples per contest.
• The Nets receive 7.2 points per game from Day'Ron Sharpe, plus 5.4 rebounds and 1.9 assists.

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