Cavaliers vs. Clippers Prediction, Odds, Picks, Best Bets for Nov. 23

Cavaliers vs. Clippers Game Info

• Date: Sunday, November 23, 2025
• Time: 6 p.m. ET
• Venue: Rocket Arena -- Cleveland, Ohio
• Coverage: FDSOH and FDSSC

Donovan Mitchell and the Cleveland Cavaliers (11-6) are 8-point favorites against James Harden and the Los Angeles Clippers (5-11) Sunday, November 23, 2025 at Rocket Arena. The game tips off at 6 p.m. ET on FDSOH and FDSSC. The point total is set at 229.5 for the matchup.

Cavaliers vs. Clippers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Cavaliers vs. Clippers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Cavaliers win (79.5%)

Cavaliers vs. Clippers Betting Trends

• The Cavaliers have covered the spread in a game six times this season (6-11-0).
• In the Clippers' 16 games this season, they have five wins against the spread.
• This season, Cavaliers games have hit the over eight times out of 16 chances.
• Clippers games this year have gone over the point total 10 times in 16 opportunities (62.5%).
• Cleveland has covered the spread in a lower percentage of its home games than away games. It has covered three times in 10 games at home, and it has covered three times in seven games when playing on the road.
• The Cavaliers have gone over the over/under in three of 10 home games (30%). They've done better on the road, topping the total in five of seven matchups (71.4%).
• In 2025-26 against the spread, Los Angeles has a lower winning percentage at home (.125, 1-7-0 record) than on the road (.500, 4-4-0).
• Both at home (five of eight) and on the road (five of eight), the Clippers' games have finished over (in terms of the over/under) 62.5% of the time.

Cavaliers Leaders

• Mitchell is averaging 30.3 points, 5.3 assists and 4.8 rebounds.
• Evan Mobley is averaging 19 points, 4 assists and 8.8 boards.
• De'Andre Hunter is averaging 18.1 points, 2.7 assists and 4.9 boards.
• Jaylon Tyson is averaging 11.3 points, 4.3 rebounds and 1.9 assists.
• Dean Wade is averaging 5.3 points, 1.5 assists and 3.9 rebounds.

Clippers Leaders

• Harden is averaging 28.4 points, 6 rebounds and 8.5 assists for the Clippers.
• Ivica Zubac's numbers on the season are 16 points, 11.2 rebounds and 2.3 assists per game. He is sinking 61.4% of his shots from the floor (10th in league).
• The Clippers receive 11.6 points per game from John Collins, plus 4.9 boards and 0.6 assists.
• Kris Dunn averages 6.9 points, 2.5 boards and 2.7 assists. He is making 47.8% of his shots from the field.
• The Clippers get 24.3 points per game from Kawhi Leonard, plus 5.7 boards and 3.5 assists.

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