Cardinals vs Rockies Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 6

Odds updated as of 2:12 p.m.

MLB action on Sunday includes the St. Louis Cardinals playing the Colorado Rockies.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's everything you need to know.

Cardinals vs Rockies Game Info

• St. Louis Cardinals (71-72) vs. Colorado Rockies (55-87)
• Date: Sunday, September 6, 2026
• Time: 3:10 p.m. ET
• Venue: Coors Field -- Denver, Colorado
• Coverage: Rockies.TV and Cardinals.TV

Cardinals vs Rockies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: STL: (-120) | COL: (+102)
• Spread: STL: -1.5 (+122) | COL: +1.5 (-146)
• Total: 10.5 -- Over: (-118) | Under: (-104)

Cardinals vs Rockies Probable Starting Pitchers

Probable Pitchers: Kyle Leahy (Cardinals) - 10-4, 3.13 ERA vs Tanner Gordon (Rockies) - 1-4, 5.18 ERA

This contest's pitching matchup is set, as the Cardinals will send Kyle Leahy (10-4) to the mound, while Tanner Gordon (1-4) will take the ball for the Rockies. Leahy and his team are 11-13-0 ATS this season when he starts. Leahy's team has a record of 4-5 this season when he starts and they are the favorite on the moneyline. The Rockies have gone 4-4-0 ATS in Gordon's eight starts that had a set spread. The Rockies are 3-5 in Gordon's eight starts this season that they were the underdog on the moneyline.

Cardinals vs Rockies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (59.8%)

Cardinals vs Rockies Moneyline

• Looking at the moneyline for Cardinals-Rockies, St. Louis is the favorite at -120, and Colorado is +102 playing at home.

Cardinals vs Rockies Spread

• The Cardinals are favored by 1.5 runs on the road against the Rockies. The Cardinals are +122 to cover the spread, while the Rockies are -146.

Cardinals vs Rockies Over/Under

• A combined run total of 10.5 has been set for Cardinals-Rockies on Sept. 6, with the over at -118 and the under at -104.

Bet on St. Louis Cardinals vs. Colorado Rockies on FanDuel today!

Cardinals vs Rockies Betting Trends

• The Cardinals have been victorious in 24, or 54.5%, of the 44 contests they have been chosen as favorites in this season.
• This season St. Louis has been victorious 14 times in 25 chances when named as a favorite of at least -120 on the moneyline.
• The Cardinals and their opponents have hit the over in 62 of their 139 games with a total set by oddsmakers this season.
• The Cardinals are 75-64-0 against the spread in their 139 games with a line set by sportsbooks this season.
• The Rockies have won 38.5% of the games this season they were the underdog on the moneyline (52-83).
• In games it has played as a moneyline underdog with odds of +102 or longer, Colorado has a record of 47-81 (36.7%).
• The Rockies have combined with opponents to hit the over on the total 66 times this season for a 66-70-3 record against the over/under.
• The Rockies have covered 54.7% of their games this season, going 76-63-0 ATS.

Cardinals Player Leaders

• Alec Burleson has 33 doubles, a triple, 21 home runs and 48 walks while hitting .280. He has an on-base percentage of .343 and a slugging percentage of .461.
• He is 22nd in batting average, 48th in on-base percentage, and 39th in slugging among qualified batters in the majors.
• Burleson has hit safely in two straight games. In his last five games he is batting .095 with two RBIs.
• Jordan Walker has 156 hits to go with a slugging percentage of .499, both of which rank first among St. Louis hitters this season. He's batting .286 with an on-base percentage of .341.
• Among all qualified batters, he ranks 14th in batting average, 51st in on-base percentage and 14th in slugging percentage.
• Ivan Herrera leads St. Louis with an OBP of .359 this season while batting .248 with 69 walks and 87 runs scored.
• Herrera heads into this matchup with three games in a row with at least one hit. During his last five outings he is batting .348 with two home runs, two walks and seven RBIs.
• Nathan Church has been key for St. Louis with 90 hits, an OBP of .285 plus a slugging percentage of .365.
• Church has safely hit in five games in a row. In his last five games he is hitting .333 with an RBI.

Rockies Player Leaders

• Jake McCarthy is batting .290 with 29 doubles, eight triples, 14 home runs and 28 walks. He's slugging .476 with an on-base percentage of .335.
• Including all qualifying hitters, he is 12th in batting average, while his on-base percentage ranks 61st and he is 30th in slugging.
• TJ Rumfield leads his team with a .387 OBP, and has a club-best .456 slugging percentage. He has a batting average of .295.
• Including all qualifying players, he ranks ninth in batting average, fifth in on-base percentage and 44th in slugging percentage.
• Hunter Goodman paces the Rockies with 114 hits.
• Troy Johnston is hitting .287 with 29 doubles, a triple, four home runs and 36 walks.

Cardinals vs Rockies Head to Head

• 9/5/2026: 10-7 COL (Favorite: Cardinals, Spread: -1.5, Total: 10.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 9/4/2026: 7-6 STL (Favorite: Cardinals, Spread: -1.5, Total: 11.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 8/9/2026: 7-4 STL (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -158, Underdog Moneyline: +146)
• 8/8/2026: 8-6 COL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +142)
• 8/7/2026: 3-2 STL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -164, Underdog Moneyline: +150)
• 8/13/2025: 6-5 COL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 8/11/2025: 3-2 STL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 7/23/2025: 6-0 COL (Favorite: Cardinals, Spread: -1.5, Total: 11, Favorite Moneyline: -186, Underdog Moneyline: +156)
• 7/22/2025: 8-4 COL (Favorite: Cardinals, Spread: -1.5, Total: 12, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 7/21/2025: 6-2 STL (Favorite: Cardinals, Spread: -1.5, Total: 11.5, Favorite Moneyline: -168, Underdog Moneyline: +142)

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