Bucks vs. Pistons Prediction, Odds, Picks, Best Bets for Nov. 22

Bucks vs. Pistons Game Info

• Date: Saturday, November 22, 2025
• Time: 8 p.m. ET
• Venue: Fiserv Forum -- Milwaukee, Wisconsin
• Coverage: FDSDET, FDSWI, and NBA TV

The Detroit Pistons (13-2) visit the Milwaukee Bucks (8-8) after winning five home road in a row. The Pistons are favored by 8 points in the contest, which tips at 8 p.m. ET on Saturday, November 22, 2025. The matchup has a point total of 224.5.

Bucks vs. Pistons Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Bucks vs. Pistons Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Bucks win (60.3%)

Bucks vs. Pistons Betting Trends

• The Pistons have covered the spread in a matchup 11 times this season (11-4-0).
• Against the spread, the Bucks are 7-9-0 this year.
• This season, eight of the Pistons' games have gone over the point total out of 16 chances.
• Bucks games this year have gone over the point total 50% of the time (eight out of 16 games with a set point total).
• In home games, Detroit sports a better record against the spread (7-2-0) compared to its ATS record on the road (4-2-0).
• In terms of over/unders, the Pistons hit the over more often at home, as they've gone over the total six times in nine opportunities this season (66.7%). On the road, they have hit the over two times in six opportunities (33.3%).
• Milwaukee's winning percentage against the spread at home is .556 (5-4-0). On the road, it is .286 (2-5-0).
• Bucks games have gone above the over/under more frequently at home (six times out of nine) than away (two of seven) this year.

Pistons Leaders

• Cade Cunningham is averaging 27.3 points, 9.9 assists and 5.4 rebounds.
• Jalen Duren's numbers on the season are 20.6 points, 11.9 rebounds and 1.8 assists per contest, shooting 67.4% from the field (sixth in league).
• Ausar Thompson's numbers on the season are 13.2 points, 6.2 boards and 3.1 assists per game, shooting 50.8% from the field.
• Duncan Robinson's numbers on the season are 12.7 points, 2.8 rebounds and 2 assists per game, shooting 44.7% from the field and 41.8% from downtown, with an average of 3.1 made treys.
• Isaiah Stewart is averaging 11.1 points, 6.5 rebounds and 1.5 assists. At the other end, he averages 0.2 steals and 2 blocked shots (fourth in league).

Bucks Leaders

• Ryan Rollins averages 18.3 points for the Bucks, plus 3.9 rebounds and 5.9 assists.
• Myles Turner averages 12.4 points, 6.5 boards and 1.8 assists. He is also sinking 43.6% of his shots from the floor and 42.4% from 3-point range, with 2.4 triples per game.
• The Bucks get 13.5 points per game from Kyle Kuzma, plus 4.3 boards and 1.9 assists.
• The Bucks receive 8.5 points per game from Cole Anthony, plus 3.3 rebounds and 5.3 assists.
• Per game, Bobby Portis gives the Bucks 10.3 points, 5.7 rebounds and 1.1 assists, plus 0.4 steals and 0.1 blocks.

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