Bills vs Lions Prediction, Odds, Picks, Best Bets for NFL Week 2 Thursday Night Football

The Buffalo Bills are among the NFL teams playing on Thursday, up against the Detroit Lions.

All the info you need is below, in order to make a smart wager on this game at FanDuel Sportsbook.

Bills vs Lions Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction:

Bills vs Lions Point Spread

The Bills are 4.5-point favorites against the Lions. The Bills are -105 to cover the spread, while the Lions are -115 to cover as a 4.5-point underdog.

Bills vs Lions Over/Under

The Bills-Lions matchup on Sept. 17 has been given an over/under of 53.5 points. The over is -115 and the under is -105.

Bills vs Lions Moneyline

Detroit is the underdog, +176 on the moneyline, while Buffalo is a -210 favorite at home.

Bills vs Lions Betting Trends

• The Bills had eight wins in 17 games against the spread last season.
• As 4.5-point favorites or more, the Bills went 4-7 against the spread last season.
• Out of 17 Buffalo games last season, nine went over the total.
• The Lions covered the spread eight times in 17 games last year.
• As 4.5-point underdogs or more, Detroit had two wins ATS (2-1) last year.
• The Lions had 10 of their 17 games go over the point total last year.

Check out even more in-depth Bills vs. Lions analysis on FanDuel Research.

Bills vs Lions Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BUF: (-210) | DET: (+176)
• Spread: BUF: -4.5 (-105) | DET: +4.5 (-115)
• Total: 53.5 -- Over: (-115) | Under: (-105)

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