Astros vs Cubs Prediction, Odds, Moneyline, Spread & Over/Under for June 29

Odds updated as of 10:12 p.m.

MLB action on Sunday includes the Houston Astros facing the Chicago Cubs.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital info about this game.

Astros vs Cubs Game Info

• Houston Astros (49-33) vs. Chicago Cubs (48-34)
• Date: Sunday, June 29, 2025
• Time: 2:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN

Astros vs Cubs Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-162) | CHC: (+136)
• Spread: HOU: -1.5 (+132) | CHC: +1.5 (-160)
• Total: 7.5 -- Over: (-120) | Under: (-102)

Astros vs Cubs Probable Starting Pitchers

Probable Pitchers: Framber Valdez (Astros) - 8-4, 2.88 ERA vs Jameson Taillon (Cubs) - 7-5, 4.47 ERA

The Astros will give the ball to Framber Valdez (8-4, 2.88 ERA), who is eyeing win No. 9 on the season, and the Cubs will turn to Jameson Taillon (7-5, 4.47 ERA). Valdez and his team have a record of 6-9-0 against the spread when he starts. Valdez's team has been victorious in 61.5% of the games he's started as the moneyline favorite with a record of 8-5. When Taillon starts, the Cubs have gone 7-8-0 against the spread. The Cubs have been the moneyline underdog in four of Taillon's starts this season, and they went 1-3 in those matchups.

Astros vs Cubs Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (58.7%)

Astros vs Cubs Moneyline

• The moneyline numbers for Astros vs. Cubs reveal Houston as the favorite (-162) and Chicago as the underdog (+136) on the road.

Astros vs Cubs Spread

• The Astros are hosting the Cubs and are favored by 1.5 runs (+132 to cover) on the runline. Chicago is -160 to cover.

Astros vs Cubs Over/Under

• The over/under for Astros-Cubs on June 29 is 7.5. The over is -120, and the under is -102.

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Astros vs Cubs Betting Trends

• The Astros have been victorious in 34, or 60.7%, of the 56 contests they have been chosen as favorites in this season.
• This year Houston has won 10 of 16 games when listed as at least -162 on the moneyline.
• The Astros and their opponents have gone over the total this season in 32 of their 81 opportunities.
• In 81 games with a line this season, the Astros have a mark of 42-39-0 against the spread.
• The Cubs have won 36% of the games this season they were the moneyline underdog (9-16).
• When it has played as a moneyline underdog with odds of +136 or longer, Chicago has a 2-2 record (winning 50% of its games).
• The Cubs have had an over/under set by oddsmakers 80 times, and have combined with opponents to go over the total in 43 of those games (43-33-4).
• The Cubs have a 40-40-0 record ATS this season.

Astros Player Leaders

• Jeremy Pena has 102 hits and an OBP of .378 to go with a slugging percentage of .489. All three of those stats rank first among Houston hitters this season. He has a .322 batting average, as well.
• Among all qualifying hitters in MLB, he ranks fourth in batting average, 17th in on-base percentage, and 29th in slugging.
• Isaac Paredes is hitting .250 with 10 doubles, a triple, 16 home runs and 42 walks. He's slugging .458 with an on-base percentage of .355.
• He is 96th in batting average, 45th in on-base percentage and 54th in slugging among qualified batters.
• Jose Altuve has collected 80 base hits, an OBP of .322 and a slugging percentage of .414 this season.
• Altuve brings a two-game hitting streak into this game. During his last five outings he is hitting .167 with three walks.
• Jake Meyers is batting .307 with a .365 OBP and 20 RBI for Houston this season.
• Meyers has hit safely in three straight games. During his last five outings he is batting .294 with a walk and an RBI.

Cubs Player Leaders

• Kyle Tucker a has .391 on-base percentage to lead the Cubs. He's batting .283 while slugging .520.
• Including all the qualified players in MLB, his batting average is 35th, his on-base percentage is seventh, and he is 14th in slugging.
• Pete Crow-Armstrong has collected 85 hits to lead his team. He has a batting average of .268 while slugging .549 with an on-base percentage of .304.
• Including all qualified hitters, his batting average places him 59th, his on-base percentage is 123rd, and he is eighth in slugging.
• Seiya Suzuki is hitting .259 with 19 doubles, two triples, 21 home runs and 28 walks.
• Nico Hoerner paces his team with a .378 slugging percentage.

Astros vs Cubs Head to Head

• 6/27/2025: 7-4 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 4/25/2024: 3-1 CHC (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 4/24/2024: 4-3 CHC (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 4/23/2024: 7-2 CHC (Favorite: Astros, Spread: -1.5, Total: 10, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/17/2023: 7-6 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 5/16/2023: 7-3 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 5/15/2023: 6-4 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -196, Underdog Moneyline: +164)

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