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Texans vs 49ers Prediction, Odds, Spread, Over/Under & Betting Trends for NFL Week 17 Game on FanDuel Sportsbook

Isaiah De Los Santos
Houston Texans vs San Francisco 49ers prediction, odds, spread, over/under and betting trends for NFL Week 17 game.
Houston Texans vs San Francisco 49ers prediction, odds, spread, over/under and betting trends for NFL Week 17 game. / Wesley Hitt/GettyImages
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Texans vs 49ers Week 17 Game Info 

NFL Regular Season — Week 17 Game
Houston Texans (4-11, 2-5 Away) vs. San Francisco 49ers (8-7, 3-4 Home)
Date: Sunday, January 2, 2022
Time: 4:05 p.m. EST
Venue: Levi's Stadium — Santa Clara, CA
Coverage: CBS

Texans vs 49ers Odds & Spread

All NFL regular betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: HOU: (+480) | SF: (-650)
Spread: HOU: +12.5 (-112) | SF: -12.5 (-108)
Total: 44.5 — Over: (-110) | Under: (-110)
Odds to Win Super Bowl LVI: HOU: (N/A) | SF: (+3100)

Texans vs 49ers Prediction & Pick

All NFL predictions and picks are from numberFire's projection model.
Prediction: 49ers win (85.8%)

Texans vs 49ers Betting Trends

- Houston is 2-4 against the spread (ATS) in its last six road games.
- The total has hit the under in five of Houston's last six road games.
- San Francisco is 5-2 ATS in its last seven games.
- The total has hit the over in five of San Francisco's last seven games.


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Isaiah De Los Santos is not a FanDuel employee. In addition to providing DFS gameplay advice, Isaiah De Los Santos also participates in DFS contests on FanDuel using his personal account, username zayyy05328. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.

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