Week 5 of the 2026 NFL season is here, and fantasy football managers have some difficult lineup decisions to make ahead of Sunday's games. With injuries piling up across the league and bye weeks starting to enter the equation, finding the right starters is more important than ever. Throw in some intriguing matchups and shifting workloads, and there are plenty of factors to consider when setting your fantasy lineup. Whether you're debating between two running backs, searching for a wide receiver with upside, or trying to find the best quarterback to stream, our Week 5 fantasy football rankings can help. Below are our updated Week 5 fantasy football rankings for quarterbacks, running backs, wide receivers, and tight ends to help you make the best start/sit decisions. Rankings compiled via our fantasy football projections. Injuries can — and will — impact these rankings