Ohio State vs Duke Prediction, Odds & Best Bet for Nov. 30 (Defenses Shine at Cameron Indoor Stadium)

Larry Rupp
Ohio State vs Duke prediction, odds and betting insights for NCAA college basketball regular season game.
Ohio State vs Duke prediction, odds and betting insights for NCAA college basketball regular season game. / AP Photos/Ben McKeown

Ohio State vs Duke Game Info

2022-23 NCAA College Basketball Regular Season Game
No. 25 Ohio State Buckeyes (5-1, 0-0 Away) vs. No. 17 Duke Blue Devils (6-2, 4-0 Home)
Date: Wednesday, Nov. 30, 2022
Time: 7:15 p.m. ET
Venue: Cameron Indoor Stadium — Durham, NC
Coverage: ESPN

The 2022-23 college basketball season continues on Wednesday with a thrilling matchup between the No. 25 Ohio State Buckeyes and No. 17 Duke Blue Devils. Ohio State is coming off an 80-73 win over Texas Tech last week. Justice Sueing dropped 33 points, 8 rebounds, and 5 assists in that one.

Meanwhile, Duke fell short in a 75-56 loss to Purdue on Sunday. The Blue Devils had the deficit within single digits before the Boilermakers went on a 12-0 run to end the game and smash any hopes of a comeback. Tyrese Proctor led the way for head coach Jon Scheyer with 16 points (7-of-13 shooting).

Ohio State vs Duke Odds & Spread

All NCAA college basketball betting lines, odds and prop bets.
Moneyline: OSU: (+190) | DUKE: (-235)
Spread: OSU: +5.5 (-110) | DUKE: -5.5 (-110)
Total: 135.5 —Over: (-108) | Under: (-112)

Duke enters this contest as clear home favorites on the moneyline and spread per FanDuel Sportsbook's odds. This 7:15 p.m. ET clash also features an over/under of 134.5 points, which is below average compared to Wednesday's projected totals.

Ohio State vs Duke Prediction & Pick

Ohio State entered the season unranked, but has shown that it is not a team to be underestimated. The Buckeyes have done an especially good job at the little things. They average only 11.5 turnovers per game (T-No. 65 in NCAA) and shoot a reliable 80.6% from the free throw line (No. 14 in NCAA).

Duke has stumbled a bit out of the gate with two losses in its first eight games, but I see this game coming down to home-court advantage. The Blue Devils have posted a 38-10 home record over the last three seasons. They are also 16-4 straight up in their last 20 games against a Big Ten opponent.

Final Score Prediction: Ohio State: 64 | Duke: 68

Ohio State vs Duke Betting Trends

- Ohio State is 6-1 straight up in its last seven games in November.
- The total has hit the over in 12 of Ohio State's last 18 away games.
- Duke is 4-1 against the spread (ATS) in its last five games on a Wednesday.
- The total has hit the under in five of Duke's last six games.

Ohio State vs Duke Best Bet

Duke basketball has become known over the years for an ability to light up the scoreboard at any time with NBA-caliber players on the court. This is not that kind of team, though. The Blue Devils have relied on defense to win games this as they allow only 57.0 points per game (T-No. 15 in NCAA).

Scheyers' squad also ranks 33rd in the nation in defensive efficiency, which is not too far ahead of the Buckeyes at 46th. Stellar defense leads to low-scoring games. The total has hit the under in five of Duke's last six games as well as in three of Ohio State's last five games. I expect the same result here.

Bet: Under 134.5 Points (-115)

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Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

Game odds refresh periodically and are subject to change.