Loyola vs Illinois Live Odds have Loyola Pulling Away as Huge Favorites for Upset Win on FanDuel Sportsbook

Loyola Chicago is now a heavy favorite in the March Madness live odds against Illinois.
Loyola Chicago is now a heavy favorite in the March Madness live odds against Illinois. / Stacy Revere/Getty Images
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The first round of the 2021 NCAA men's basketball tournament was one of the wildest in recent memory, with a record number of high-seed upsets.

That chaos appears to be continuing in the second round. With 10 minutes left in the second half, Loyola Chicago is up 49-38 over Illinois.

As of writing, the live odds on FanDuel Sportsbook for this game now have Loyola as all but a lock to take home the upset victory.

Loyola is a whopping -550 moneyline favorite, sitting favored by a 6.5-point spread.

Loyola had gone 4-1 against the spread (ATS) in their last five games prior to this one, but only 14% of the spread bets had come in on them.

Loyola will certainly be busting some brackets if they hang on to this win, while also making this a great start to the round for anyone who bet on the upset.


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Jason Schandl is not a FanDuel employee. In addition to providing DFS gameplay advice, Jason Schandl also participates in DFS contests on FanDuel using his personal account, username Jaymun. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in his articles are the author's alone and do not necessarily reflect the views of FanDuel.