Clemson vs Iowa State Latest Odds, Betting Lines and Prediction for College Football Cheez-It Bowl on FanDuel

Devon Platana
Clemson vs Iowa State NCAAF latest odds, lines and predictions for Cheez-It Bowl.
Clemson vs Iowa State NCAAF latest odds, lines and predictions for Cheez-It Bowl. / Jacob Kupferman/GettyImages
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The No. 19 Clemson Tigers will go head-to-head against the Iowa State Cyclones in the 2021 Cheez-It Bowl. This year's bowl game will be played at Camping World Stadium in Orlando, FL on Wednesday, Dec. 29 at 5:45 p.m. EST.

Here's everything you need to know about the latest odds and predictions heading into the Cheez-It Bowl.

Clemson vs Iowa State Cheez-It Bowl Odds & Lines

All NCAAF betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: CLEM: (+100) | ISU: (-122)
Spread: CLEM: +1.5 (-110) | ISU: -1.5 (-110)
Total: 45 — Over: (-110) | Under: (-110)

The odds have shifted just a little bit since the opening ones were posted on Dec. 6. At the time, both teams had -110 monleyline odds, while the total sat at 44.5.

Clemson vs Iowa State Cheez-It Bowl Prediction

All NCAAF predictions & expert picks are according to numberFire.
Prediction: Iowa State Cyclones (64.4%)

Clemson vs Iowa State Best Bet

That projection from numberFire leaves Clemson with a 35.6% chance of winning this game. Converted to moneyline odds, that would translate to +180. Since the actual odds are lower (+100), the Iowa State moneyline is the best projected bet for the Cheez-It Bowl.


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Devon Platana is not a FanDuel employee. The views expressed in his articles are the author's alone and do not necessarily reflect the views of FanDuel.

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