49ers vs Titans Predictions and Expert Picks for Week 16 NFL Thursday Night Football From FanDuel Sportsbook

Week 16's slate of NFL games includes a Thursday Night Football clash between the San Francisco 49ers and Tennessee Titans.

49ers vs Titans Prediction and Pick

ESPN picks are from their Football Power Index (FPI) matchup predictor, numberFire picks are from their analytics projection models, FiveThirtyEight picks are from their NFL projections and betting favorites are according to FanDuel Sportsbook's 49ers-Titans betting odds and lines.

NFL Week 16 Picks Straight Up

ESPN: 49ers
numberFire: 49ers
FiveThirtyEight: Titans
Betting Favorite: 49ers (-3)

Titans vs 49ers Prediction

Winner: 49ers (3), Titans (1)

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Adam Taylor McKillop is not a FanDuel employee. In addition to providing DFS gameplay advice, Adam Taylor also participates in DFS contests on FanDuel using his personal account, username atmckillop. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.