49ers vs Seahawks Opening Odds, Betting Lines and Prediction for Week 13 Game on FanDuel Sportsbook

Larry Rupp
San Francisco 49ers vs Seattle Seahawks NFL opening odds, lines and predictions for Week 13 matchup.
San Francisco 49ers vs Seattle Seahawks NFL opening odds, lines and predictions for Week 13 matchup. / Douglas P. DeFelice/GettyImages
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Week 12 NFL action has yet to wrap up, but FanDuel Sportsbook has already released NFL odds and lines for Week 13, giving us an early preview of next week's games.

Week 13's slate features an NFC West clash between the San Francisco 49ers and Seattle Seahawks.

49ers vs Seahawks Odds & Lines Week 13

All NFL betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: SF: (-154) | SEA: (+130)
Spread: SF: -2.5 (-115) | SEA: +2.5 (-105)
Total: N/A — Over: (N/A) | Under: (N/A)

49ers vs Seahawks Prediction Week 13

Early NFL predictions and picks are from ESPN's Football Power Index (FPI).
49ers: 50.2% to win
Seahawks: 49.4% to win


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Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

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