49ers vs Packers Prediction, Odds, Spread, Over/Under & Betting Trends for NFL NFC Divisional Game on FanDuel

Larry Rupp
San Francisco 49ers vs Green Bay Packers prediction, odds, spread, over/under and betting trends for NFL NFC Divisional game.
San Francisco 49ers vs Green Bay Packers prediction, odds, spread, over/under and betting trends for NFL NFC Divisional game. / Patrick McDermott/GettyImages
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49ers vs Packers Divisional Game Info

NFL Playoffs — Divisional Round
San Francisco 49ers (10-7, 6-3 Away) vs. Green Bay Packers (13-4, 8-0 Home)
Date: Saturday, January 22, 2022
Time: 8:15 p.m. EST
Venue: Lambeau Field — Green Bay, WI
Coverage: FOX

49ers vs Packers Odds & Spread

All NFL regular betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: SF: (+198) | GB: (-240)
Spread: SF: +4.5 (-104) | GB: -4.5 (-118)
Total: 47.5 — Over: (-112) | Under: (-108)
Odds to Win Super Bowl LVI: SF: (+1000) | GB: (+370)

49ers vs Packers Prediction & Pick

All NFL predictions and picks are from numberFire's projection model and will be updated when available.
Prediction: N/A

49ers vs Packers Betting Trends

- San Francisco is 5-1 against the spread (ATS) in its last six games.
- The total has hit the under in five of San Francisco's last six games.
- Green Bay is 12-6 straight up in its last 18 games against San Francisco.
- The total has hit the over in four of Green Bay's last five games against San Francisco.


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Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

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