White Sox vs Tigers Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 20

Odds updated as of 1:11 p.m.

In MLB action on Sunday, the Chicago White Sox take on the Detroit Tigers.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

White Sox vs Tigers Game Info

• Chicago White Sox (79-76) vs. Detroit Tigers (73-82)
• Date: Sunday, September 20, 2026
• Time: 2:10 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and DSN

White Sox vs Tigers Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHW: (-118) | DET: (+100)
• Spread: CHW: +1.5 (-205) | DET: -1.5 (+168)
• Total: 7.5 -- Over: (-134) | Under: (+110)

White Sox vs Tigers Probable Starting Pitchers

Probable Pitchers: Davis Martin (White Sox) - 9-7, 3.96 ERA vs Troy Melton (Tigers) - 8-4, 2.52 ERA

The probable pitchers are Davis Martin (9-7) for the White Sox and Troy Melton (8-4) for the Tigers. Martin's team is 13-13-0 against the spread this season in his starts. Martin's team has a record of 3-4 this season when he starts and they are the favorite on the moneyline. When Melton starts, the Tigers have gone 10-8-0 against the spread. The Tigers have been the moneyline underdog in seven of Melton's starts this season, and they went 5-2 in those games.

White Sox vs Tigers Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Tigers win (51.2%)

White Sox vs Tigers Moneyline

• Detroit is the underdog, +100 on the moneyline, while Chicago is a -118 favorite at home.

White Sox vs Tigers Spread

• The Tigers are 1.5-run favorites against the spread for this matchup with the White Sox. The Tigers are +168 to cover, while the White Sox are -205 to cover as a 1.5-run underdog on the runline.

White Sox vs Tigers Over/Under

• White Sox versus Tigers on Sept. 20 has an over/under of 7.5 runs, with the odds on the over -134 and the under set at +110.

Bet on Chicago White Sox vs. Detroit Tigers on FanDuel today!

White Sox vs Tigers Betting Trends

• The White Sox have come away with 21 wins in the 39 contests they have been listed as the favorites in this season.
• Chicago has a record of 16-13 when favored by -118 or more this year.
• Contests with the White Sox have gone over the total set by oddsmakers in 84 of 152 chances this season.
• The White Sox have posted a record of 85-67-0 against the spread this season.
• The Tigers have been the underdog on the moneyline 66 total times this season. They've gone 29-37 in those games.
• Detroit is 24-29 (winning 45.3% of its games) when it has played as a moneyline underdog of +100 or longer.
• The Tigers have played in 149 games with an over/under set, and have combined with their opponents to go over the total 65 times (65-81-3).
• The Tigers have covered 51.7% of their games this season, going 77-72-0 against the spread.

White Sox Player Leaders

• Miguel Vargas has 142 hits, which is best among Chicago hitters this season, while batting .250 with 65 extra-base hits. He has an on-base percentage of .359 and a slugging percentage of .482.
• Among qualifying hitters in baseball, his batting average ranks 77th, his on-base percentage ranks 32nd, and he is 25th in slugging.
• Vargas hopes to build on a two-game hitting streak in this matchup. In his last five games he is hitting .294 with a double, two home runs, four walks and seven RBIs.
• Chase Meidroth has hit 14 homers this season while driving in 56 runs. He's batting .268 this season and slugging .398 with an on-base percentage of .345.
• He ranks 44th in batting average, 48th in on-base percentage and 90th in slugging among qualified hitters.
• Sam Antonacci has 122 hits this season and a team-best OBP of .362.
• Tristan Peters has been key for Chicago with 114 hits, an OBP of .344 plus a slugging percentage of .451.

Tigers Player Leaders

• Kevin McGonigle has accumulated a team-high OBP (.377) and slugging percentage (.427). He's batting .276.
• He is 32nd in batting average, 10th in on-base percentage and 65th in slugging percentage among all qualified hitters in the majors.
• McGonigle takes a four-game hitting streak into this game. In his last five games he is batting .368 with a triple, five walks and five RBIs.
• Riley Greene's 140 hits pace his team. He has a batting average of .286 while slugging .484 with an on-base percentage of .373.
• Including all qualifying players, he ranks 14th in batting average, 13th in on-base percentage and 23rd in slugging percentage.
• Dillon Dingler is batting .243 with 26 doubles, two triples, 27 home runs and 32 walks.
• Spencer Torkelson is hitting .228 with 26 doubles, 24 home runs and 66 walks.

White Sox vs Tigers Head to Head

• 9/19/2026: 3-1 CHW (Favorite: White Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 9/18/2026: 11-8 DET (Favorite: White Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/17/2026: 3-1 CHW (Favorite: White Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/16/2026: 7-5 CHW (Favorite: Tigers, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: +102)
• 8/15/2026: 4-3 CHW (Favorite: Tigers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +126)
• 8/14/2026: 9-5 CHW (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -128, Underdog Moneyline: +120)
• 6/21/2026: 5-4 DET (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/20/2026: 4-1 DET (Favorite: Tigers, Spread: -1.5, Total: 9, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/19/2026: 4-3 DET (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 5/31/2026: 2-1 CHW (Favorite: White Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)

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