White Sox vs Tigers Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 18

Odds updated as of 7:12 p.m.

The MLB's Friday schedule includes the Chicago White Sox facing the Detroit Tigers.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important info regarding this matchup.

White Sox vs Tigers Game Info

• Chicago White Sox (78-75) vs. Detroit Tigers (72-81)
• Date: Friday, September 18, 2026
• Time: 7:40 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and DSN

White Sox vs Tigers Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHW: (-130) | DET: (+110)
• Spread: CHW: -1.5 (+158) | DET: +1.5 (-192)
• Total: 8.5 -- Over: (+100) | Under: (-122)

White Sox vs Tigers Probable Starting Pitchers

Probable Pitchers: David Sandlin (White Sox) - 2-2, 5.64 ERA vs Andrew Sears (Tigers) - 0-1, 5.40 ERA

The probable pitchers are David Sandlin (2-2) for the White Sox and Andrew Sears (0-1) for the Tigers. Sandlin's team is 2-2-0 against the spread in his starts this season. Sandlin's team is 1-1 this season when he starts and they're favored on the moneyline. Sears has started only one game with a set spread, which the Tigers covered. The Tigers have not been a moneyline underdog when Sears starts this season.

White Sox vs Tigers Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: White Sox win (51.5%)

White Sox vs Tigers Moneyline

• The moneyline numbers for White Sox vs. Tigers reveal Chicago as the favorite (-130) and Detroit as the underdog (+110) on the road.

White Sox vs Tigers Spread

• The White Sox are hosting the Tigers and are favored by 1.5 runs (+158 to cover) on the runline. Detroit is -192 to cover.

White Sox vs Tigers Over/Under

• An over/under of 8.5 has been set for White Sox-Tigers on Sept. 18, with the over being +100 and the under -122.

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White Sox vs Tigers Betting Trends

• The White Sox have come away with 20 wins in the 37 contests they have been listed as the favorites in this season.
• This season Chicago has been victorious seven times in 13 chances when named as a favorite of at least -130 on the moneyline.
• Contests with the White Sox have gone over the total set by bookmakers in 83 of 150 chances this season.
• The White Sox have an against the spread mark of 84-66-0 in 150 games with a line this season.
• The Tigers have won 28 of the 64 games they were listed as the moneyline underdog this season (43.8%).
• When playing as a moneyline underdog with odds of +110 or longer, Detroit has a record of 12-17 (41.4%).
• The Tigers have played in 147 games with a set over/under, and have combined with opponents to go over the total 64 times (64-80-3).
• The Tigers have a 76-71-0 record ATS this season (covering 51.7% of the time).

White Sox Player Leaders

• Miguel Vargas leads Chicago with 139 hits, batting .248 this season with 62 extra-base hits. He has an on-base percentage of .356 and a slugging percentage of .471.
• Among qualified hitters, he ranks 82nd in batting average, his on-base percentage ranks 35th, and he is 30th in slugging.
• Chase Meidroth has an OPS of .747, fueled by an OBP of .345 and a team-best slugging percentage of .401 this season. He's batting .271.
• Among qualifiers, he ranks 40th in batting average, 49th in on-base percentage and 89th in slugging percentage.
• Meidroth brings a four-game streak with at least one hit into this matchup. In his last five games he is hitting .350 with two doubles, a walk and three RBIs.
• Sam Antonacci leads Chicago with an OBP of .367 this season while batting .271 with 42 walks and 75 runs scored.
• Tristan Peters has been key for Chicago with 114 hits, an OBP of .343 plus a slugging percentage of .452.

Tigers Player Leaders

• Kevin McGonigle has racked up an on-base percentage of .377 and a slugging percentage of .425. Both lead the Tigers. He's batting .275.
• Including all the qualified hitters in MLB, his batting average ranks 35th, his on-base percentage ranks 10th, and he is 67th in slugging.
• Riley Greene has 137 hits to lead his team. He has a batting average of .284 while slugging .478 with an on-base percentage of .370.
• He is 16th in batting average, 15th in on-base percentage and 27th in slugging percentage in the big leagues.
• Dillon Dingler is batting .242 with 26 doubles, two triples, 27 home runs and 32 walks.
• Spencer Torkelson is hitting .227 with 26 doubles, 24 home runs and 65 walks.

White Sox vs Tigers Head to Head

• 9/17/2026: 3-1 CHW (Favorite: White Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/16/2026: 7-5 CHW (Favorite: Tigers, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: +102)
• 8/15/2026: 4-3 CHW (Favorite: Tigers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +126)
• 8/14/2026: 9-5 CHW (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -128, Underdog Moneyline: +120)
• 6/21/2026: 5-4 DET (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/20/2026: 4-1 DET (Favorite: Tigers, Spread: -1.5, Total: 9, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/19/2026: 4-3 DET (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 5/31/2026: 2-1 CHW (Favorite: White Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/30/2026: 7-1 CHW (Favorite: Tigers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/29/2026: 4-3 CHW (Favorite: White Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -108, Underdog Moneyline: -108)

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