White Sox vs Tigers Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 17

Odds updated as of 7:13 p.m.

The Chicago White Sox will face the Detroit Tigers in MLB action on Thursday.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

White Sox vs Tigers Game Info

• Chicago White Sox (77-75) vs. Detroit Tigers (72-80)
• Date: Thursday, September 17, 2026
• Time: 7:40 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and DSN

White Sox vs Tigers Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHW: (-112) | DET: (-104)
• Spread: CHW: +1.5 (-188) | DET: -1.5 (+155)
• Total: 8.5 -- Over: (-108) | Under: (-112)

White Sox vs Tigers Probable Starting Pitchers

Probable Pitchers: Erick Fedde (White Sox) - 8-9, 3.97 ERA vs Framber Valdez (Tigers) - 10-10, 4.01 ERA

This contest's pitching matchup is set, as the White Sox will send Erick Fedde (8-9) to the mound, while Framber Valdez (10-10) will get the nod for the Tigers. Fedde's team is 10-4-0 against the spread this season in his starts. Fedde's team is 2-0 this season when he starts and they're favored on the moneyline. The Tigers are 13-14-0 ATS in Valdez's 27 starts with a set spread. The Tigers have a 7-5 record in Valdez's 12 starts this season when they were the moneyline underdog.

White Sox vs Tigers Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Tigers win (56%)

White Sox vs Tigers Moneyline

• Looking at the moneyline for White Sox-Tigers, Chicago is the favorite at -112, and Detroit is -104 playing on the road.

White Sox vs Tigers Spread

• The Tigers are 1.5-run favorites against the spread for this matchup with the White Sox. The Tigers are +155 to cover, while the White Sox are -188 to cover as a 1.5-run underdog on the runline.

White Sox vs Tigers Over/Under

• The over/under for White Sox-Tigers on Sept. 17 is 8.5. The over is -108, and the under is -112.

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White Sox vs Tigers Betting Trends

• The White Sox have been victorious in 19, or 52.8%, of the 36 contests they have been chosen as favorites in this season.
• This season Chicago has been victorious 18 times in 34 chances when named as a favorite of at least -112 on the moneyline.
• The White Sox and their opponents have gone over in 83 of their 149 games with a total set by sportsbooks this season.
• The White Sox are 83-66-0 against the spread in their 149 games with a line set by sportsbooks this season.
• The Tigers have a 28-35 record in games they were the underdog on the moneyline (winning 44.4% of those games).
• Detroit has a 27-33 record (winning 45% of its games) when playing as a moneyline underdog of -104 or longer.
• The Tigers have played in 146 games with a set over/under, and have combined with opponents to go over the total 64 times (64-79-3).
• The Tigers have a 76-70-0 record against the spread this season.

White Sox Player Leaders

• Miguel Vargas leads Chicago in total hits (139) this season while batting .249 with 62 extra-base hits. He has an on-base percentage of .357 and a slugging percentage of .473.
• Among all qualifying batters in MLB, he ranks 81st in batting average, 35th in on-base percentage, and 30th in slugging.
• Vargas hopes to build on a six-game hitting streak in this matchup. In his last 10 games he is hitting .225 with a home run, four walks and six RBIs.
• Chase Meidroth leads Chicago in slugging percentage (.403) thanks to 43 extra-base hits. He's batting .271 with an on-base percentage of .346.
• Among all qualified hitters, he is 40th in batting average, 48th in on-base percentage and 88th in slugging percentage.
• Meidroth has picked up at least one hit in three straight games. During his last five outings he is batting .316 with two doubles, two walks and three RBIs.
• Sam Antonacci has 122 hits this season and a team-best OBP of .367.
• Tristan Peters has been key for Chicago with 114 hits, an OBP of .343 plus a slugging percentage of .452.

Tigers Player Leaders

• Kevin McGonigle has accumulated a team-best OBP (.376) and slugging percentage (.424). He's batting .274.
• Including all qualifying hitters in the big leagues, his batting average places him 35th, his on-base percentage is 10th, and he is 69th in slugging.
• Riley Greene has collected 136 hits to lead his team. He has a batting average of .284 while slugging .480 with an on-base percentage of .371.
• Including all qualified players, he ranks 16th in batting average, 16th in on-base percentage and 27th in slugging percentage.
• Dillon Dingler is batting .242 with 25 doubles, two triples, 27 home runs and 32 walks.
• Spencer Torkelson is batting .226 with 26 doubles, 24 home runs and 64 walks.

White Sox vs Tigers Head to Head

• 8/16/2026: 7-5 CHW (Favorite: Tigers, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: +102)
• 8/15/2026: 4-3 CHW (Favorite: Tigers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +126)
• 8/14/2026: 9-5 CHW (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -128, Underdog Moneyline: +120)
• 6/21/2026: 5-4 DET (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/20/2026: 4-1 DET (Favorite: Tigers, Spread: -1.5, Total: 9, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/19/2026: 4-3 DET (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 5/31/2026: 2-1 CHW (Favorite: White Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/30/2026: 7-1 CHW (Favorite: Tigers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/29/2026: 4-3 CHW (Favorite: White Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 9/7/2025: 6-4 CHW (Favorite: Tigers, Spread: -1.5, Total: 9, Favorite Moneyline: -178, Underdog Moneyline: +150)

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