White Sox vs Royals Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 24

Odds updated as of 1:11 p.m.

MLB action on Thursday includes the Chicago White Sox facing the Kansas City Royals.

All the information you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

White Sox vs Royals Game Info

• Chicago White Sox (81-77) vs. Kansas City Royals (68-90)
• Date: Thursday, September 24, 2026
• Time: 2:10 p.m. ET
• Venue: Kauffman Stadium -- Kansas City, Missouri
• Coverage: Royals.TV and CHSN

White Sox vs Royals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHW: (-132) | KC: (+112)
• Spread: CHW: -1.5 (+126) | KC: +1.5 (-152)
• Total: 8.5 -- Over: (-122) | Under: (+100)

White Sox vs Royals Probable Starting Pitchers

Probable Pitchers: David Sandlin (White Sox) - 2-2, 6.29 ERA vs Randy Dobnak (Royals) - 3-4, 3.08 ERA

The White Sox will give the ball to David Sandlin (2-2, 6.29 ERA), who is eyeing win No. 3 on the season, and the Royals will counter with Randy Dobnak (3-4, 3.08 ERA). Sandlin and his team are 2-3-0 ATS this season when he starts. Sandlin's team is 1-2 this season when he starts and they are the moneyline favorite. The Royals have a 7-5-0 record against the spread in Dobnak's starts. The Royals have been the underdog on the moneyline in 10 of Dobnak's starts this season, and they went 4-6 in those matchups.

White Sox vs Royals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Royals win (51.2%)

White Sox vs Royals Moneyline

• Chicago is a -132 favorite on the moneyline, while Kansas City is a +112 underdog at home.

White Sox vs Royals Spread

• The White Sox are at the Royals and are favored by 1.5 runs (+126 to cover) on the runline. Kansas City is -152 to cover.

White Sox vs Royals Over/Under

• An over/under of 8.5 has been set for White Sox-Royals on Sept. 24, with the over being -122 and the under +100.

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White Sox vs Royals Betting Trends

• The White Sox have won in 23, or 54.8%, of the 42 contests they have been named as odds-on favorites in this year.
• This season Chicago has been victorious five times in 10 chances when named as a favorite of at least -132 on the moneyline.
• The White Sox and their opponents have hit the over in 87 of their 155 games with a total set by oddsmakers this season.
• The White Sox have posted a record of 87-68-0 against the spread this season.
• The Royals have been the moneyline underdog 100 total times this season. They've gone 39-61 in those games.
• In games it has played as a moneyline underdog with odds of +112 or longer, Kansas City has a record of 20-35 (36.4%).
• The Royals have had an over/under set by bookmakers 151 times, and have combined with opponents to go over the total in 69 of those games (69-79-3).
• The Royals have covered 50.3% of their games this season, going 76-75-0 against the spread.

White Sox Player Leaders

• Miguel Vargas leads Chicago with 145 hits, batting .251 this season with 65 extra-base hits. He has an on-base percentage of .362 and a slugging percentage of .479.
• He ranks 79th in batting average, 26th in on-base percentage, and 25th in slugging among qualified hitters in MLB.
• Vargas hopes to build on a five-game hitting streak in this matchup. In his last five games he is hitting .353 with a double, two home runs, six walks and six RBIs.
• Chase Meidroth has an OPS of .758, fueled by an OBP of .348 and a team-best slugging percentage of .410 this season. He's batting .273.
• Among qualifying hitters, his batting average places him 37th, his on-base percentage 43rd, and his slugging percentage 81st.
• Meidroth heads into this game looking to extend his three-game hit streak. In his last five games he is batting .333 with two home runs, two walks and seven RBIs.
• Sam Antonacci has 125 hits this season and a team-best OBP of .364.
• Antonacci enters this game with two games in a row with at least one hit. During his last five outings he is hitting .214 with a double and three RBIs.
• Tristan Peters has been key for Chicago with 114 hits, an OBP of .342 plus a slugging percentage of .447.

Royals Player Leaders

• Bobby Witt Jr. has racked up a team-best OBP (.361) and slugging percentage (.443). He's batting .282.
• He is 19th in batting average, 28th in on-base percentage and 52nd in slugging percentage among all qualifying hitters in MLB.
• Witt heads into this matchup on a five-game hitting streak. In his last five games he is batting .429 with a double.
• Carter Jensen is batting .237 with 33 doubles, two triples, 25 home runs and 64 walks. He's slugging .454 with an on-base percentage of .323.
• Including all qualifying players, his batting average puts him 102nd, his on-base percentage is 83rd, and he is 40th in slugging.
• Jac Caglianone has accumulated 141 hits, a team-high for the Royals.
• Vinnie Pasquantino has 20 doubles, two triples, 15 home runs and 50 walks while batting .249.

White Sox vs Royals Head to Head

• 9/23/2026: 5-4 KC (Favorite: White Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/22/2026: 14-11 CHW (Favorite: White Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: +100)
• 6/28/2026: 5-4 KC (Favorite: White Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 6/27/2026: 2-1 CHW (Favorite: White Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/26/2026: 22-1 CHW (Favorite: White Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/14/2026: 6-2 CHW (Favorite: Royals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 5/13/2026: 6-5 CHW (Favorite: Royals, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/12/2026: 6-5 CHW (Favorite: Royals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 4/11/2026: 2-0 KC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 4/10/2026: 2-0 KC (Favorite: Royals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -180, Underdog Moneyline: +152)

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