White Sox vs Royals Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 24

Odds updated as of 1:11 a.m.

In MLB action on Thursday, the Chicago White Sox take on the Kansas City Royals.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital info regarding this matchup.

White Sox vs Royals Game Info

• Chicago White Sox (81-77) vs. Kansas City Royals (68-90)
• Date: Thursday, September 24, 2026
• Time: 2:10 p.m. ET
• Venue: Kauffman Stadium -- Kansas City, Missouri
• Coverage: Royals.TV and CHSN

White Sox vs Royals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHW: (-130) | KC: (+110)
• Spread: CHW: -1.5 (+128) | KC: +1.5 (-154)
• Total: 8.5 -- Over: (-142) | Under: (+116)

White Sox vs Royals Probable Starting Pitchers

Probable Pitchers: David Sandlin (White Sox) - 2-2, 6.29 ERA vs Randy Dobnak (Royals) - 3-4, 3.08 ERA

The White Sox will give the nod to David Sandlin (2-2, 6.29 ERA), who is eyeing win No. 3 on the season, and the Royals will turn to Randy Dobnak (3-4, 3.08 ERA). Sandlin's team is 2-3-0 against the spread in his starts this season. Sandlin's team has a record of 1-2 this season when he starts and they are the favorite on the moneyline. The Royals are 7-5-0 against the spread when Dobnak starts. The Royals have been the underdog on the moneyline in 10 of Dobnak's starts this season, and they went 4-6 in those matchups.

White Sox vs Royals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Royals win (50.8%)

White Sox vs Royals Moneyline

• Chicago is a -130 favorite on the moneyline, while Kansas City is a +110 underdog at home.

White Sox vs Royals Spread

• The White Sox are at the Royals and are favored by 1.5 runs on the spread. The White Sox are +128 to cover the runline, with the Royals being -154.

White Sox vs Royals Over/Under

• The over/under for the White Sox versus Royals game on Sept. 24 has been set at 8.5, with -142 odds on the over and +116 odds on the under.

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White Sox vs Royals Betting Trends

• The White Sox have been chosen as favorites in 42 games this year and have walked away with the win 23 times (54.8%) in those games.
• This year Chicago has won seven of 14 games when listed as at least -130 on the moneyline.
• The White Sox's games have gone over the total in 87 of their 155 opportunities.
• The White Sox have an against the spread record of 87-68-0 in 155 games with a line this season.
• The Royals have won 39% of the games this season they were the underdog on the moneyline (39-61).
• When it has played as a moneyline underdog with odds of +110 or longer, Kansas City has gone 21-35 (37.5%).
• In the 151 games bookmakers have set an over/under for the Royals, they have combined with opponents to go over the total 69 times (69-79-3).
• The Royals have put together a 76-75-0 record against the spread this season.

White Sox Player Leaders

• Miguel Vargas leads Chicago with 145 hits, batting .251 this season with 65 extra-base hits. He has an on-base percentage of .362 and a slugging percentage of .479.
• Among qualifying hitters in the majors, he is 78th in batting average, 26th in on-base percentage, and 26th in slugging.
• Vargas will look for his sixth straight game with a hit in this contest. During his last five outings he is hitting .353 with a double, two home runs, six walks and six RBIs.
• Chase Meidroth leads Chicago in slugging percentage (.410) thanks to 45 extra-base hits. He's batting .273 with an on-base percentage of .348.
• He ranks 36th in batting average, 44th in on-base percentage and 81st in slugging among qualified batters.
• Meidroth takes a three-game streak with at least one hit into this contest. In his last five games he is hitting .333 with two home runs, two walks and seven RBIs.
• Sam Antonacci leads Chicago with an OBP of .364 this season while batting .269 with 42 walks and 77 runs scored.
• Antonacci heads into this game with two games in a row with at least one hit. In his last five games he is batting .214 with a double and three RBIs.
• Tristan Peters is batting .270 with a .342 OBP and 54 RBI for Chicago this season.

Royals Player Leaders

• Bobby Witt Jr. has put up a team-high OBP (.361) and slugging percentage (.443). He's batting .282.
• Including all qualified hitters, he ranks 19th in batting average, while his on-base percentage is 28th and he is 52nd in slugging.
• Witt hopes to build on a five-game hitting streak in this matchup. In his last five games he is hitting .429 with a double.
• Carter Jensen is hitting .237 with 33 doubles, two triples, 25 home runs and 64 walks. He's slugging .454 with an on-base percentage of .323.
• His batting average is 102nd among all qualified players, his on-base percentage is 83rd, and he is 40th in slugging.
• Jac Caglianone leads the Royals with 141 hits.
• Vinnie Pasquantino is hitting .249 with 20 doubles, two triples, 15 home runs and 50 walks.

White Sox vs Royals Head to Head

• 9/23/2026: 5-4 KC (Favorite: White Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/22/2026: 14-11 CHW (Favorite: White Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: +100)
• 6/28/2026: 5-4 KC (Favorite: White Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 6/27/2026: 2-1 CHW (Favorite: White Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/26/2026: 22-1 CHW (Favorite: White Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/14/2026: 6-2 CHW (Favorite: Royals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 5/13/2026: 6-5 CHW (Favorite: Royals, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/12/2026: 6-5 CHW (Favorite: Royals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 4/11/2026: 2-0 KC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 4/10/2026: 2-0 KC (Favorite: Royals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -180, Underdog Moneyline: +152)

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