White Sox vs Rockies Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 27

Odds updated as of 2:13 p.m.

The MLB schedule on Sunday includes the Chicago White Sox taking on the Colorado Rockies.

We've got you covered, in terms of the vital information about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

White Sox vs Rockies Game Info

• Chicago White Sox (83-78) vs. Colorado Rockies (58-103)
• Date: Sunday, September 27, 2026
• Time: 3:10 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and Rockies.TV

White Sox vs Rockies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHW: (-164) | COL: (+138)
• Spread: CHW: -1.5 (+122) | COL: +1.5 (-146)
• Total: 8.5 -- Over: (+100) | Under: (-122)

White Sox vs Rockies Probable Starting Pitchers

Probable Pitchers: Anthony Kay (White Sox) - 9-9, 4.59 ERA vs Kyle Freeland (Rockies) - 4-11, 6.58 ERA

The White Sox will give the nod to Anthony Kay (9-9, 4.59 ERA), who is eyeing win No. 10 on the season, and the Rockies will counter with Kyle Freeland (4-11, 6.58 ERA). Kay's team is 19-10-0 against the spread this season in his starts. Kay's team is 2-3 this season when he starts and they are the moneyline favorite. The Rockies are 13-13-0 ATS in Freeland's 26 starts that had a set spread. The Rockies have been the moneyline underdog in 25 of Freeland's starts this season, and they went 9-16 in those games.

White Sox vs Rockies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: White Sox win (66.6%)

White Sox vs Rockies Moneyline

• Looking at the moneyline for Rockies-White Sox, Colorado is the underdog at +138, and Chicago is -164 playing at home.

White Sox vs Rockies Spread

• The Rockies are at the White Sox, and are +1.5 on the runline. The Rockies are +122 to cover the spread, and the White Sox are -146.

White Sox vs Rockies Over/Under

• The over/under for White Sox-Rockies on Sept. 27 is 8.5. The over is +100, and the under is -122.

Bet on Chicago White Sox vs. Colorado Rockies on FanDuel today!

White Sox vs Rockies Betting Trends

• The White Sox have been chosen as favorites in 45 games this year and have walked away with the win 25 times (55.6%) in those games.
• Chicago has a record of 3-1 in contests when oddsmakers favor them by -164 or more on the moneyline.
• The White Sox and their opponents have gone over in 89 of their 158 games with a total set by sportsbooks this season.
• In 158 games with a line this season, the White Sox have a mark of 89-69-0 against the spread.
• The Rockies have won 35.7% of the games this season they were the moneyline underdog (55-99).
• Colorado has a 26-68 record (winning only 27.7% of its games) when it has played as a moneyline underdog of +138 or longer.
• The Rockies have played in 158 games with an over/under set, and have combined with opponents to go over the total 77 times (77-78-3).
• The Rockies have put together an 82-76-0 record ATS this season (covering 51.9% of the time).

White Sox Player Leaders

• Miguel Vargas has 31 doubles, a triple, 33 home runs and 101 walks while hitting .250. He has an on-base percentage of .363 and a slugging percentage of .474.
• Among all qualified batters in MLB, his batting average ranks 77th, his on-base percentage ranks 25th, and he is 29th in slugging.
• Chase Meidroth leads Chicago in slugging percentage (.415) thanks to 47 extra-base hits. He's batting .276 with an on-base percentage of .350.
• Among qualified hitters, his batting average places him 31st, his on-base percentage 42nd, and his slugging percentage 79th.
• Meidroth enters this game looking to extend his five-game hit streak. In his last five games he is batting .500 with two doubles, two home runs, a walk and seven RBIs.
• Sam Antonacci leads Chicago in OBP (.367) this season, fueled by 131 hits.
• Antonacci takes a five-game hitting streak into this matchup. In his last five games he is batting .429 with a double, a walk and two RBIs.
• Munetaka Murakami leads Chicago in total hits (93) this season while batting .207 with 51 extra-base hits.

Rockies Player Leaders

• Jake McCarthy is batting .292 with 30 doubles, 13 triples, 15 home runs and 30 walks. He's slugging .478 with an on-base percentage of .336.
• Including all the qualifying hitters in the majors, his batting average ranks 10th, his on-base percentage ranks 60th, and he is 26th in slugging.
• TJ Rumfield has a .390 OBP while slugging .453. Both lead his team. He has a batting average of .300.
• Including all qualifying hitters, he ranks seventh in batting average, second in on-base percentage and 45th in slugging percentage.
• Hunter Goodman has racked up 127 hits, a team-high for the Rockies.
• Kyle Karros is hitting .253 with 21 doubles, three triples, 13 home runs and 54 walks.

White Sox vs Rockies Head to Head

• 9/26/2026: 9-6 COL (Favorite: White Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 9/25/2026: 6-1 CHW (Favorite: White Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -250, Underdog Moneyline: +205)
• 7/6/2025: 6-4 COL (Favorite: White Sox, Spread: -1.5, Total: 11, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 7/5/2025: 10-3 CHW (Favorite: Rockies, Spread: -1.5, Total: 11, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 7/4/2025: 3-2 CHW (Favorite: White Sox, Spread: -1.5, Total: 11, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/30/2024: 5-4 COL (Favorite: White Sox, Spread: -1.5, Total: 7, Favorite Moneyline: -230, Underdog Moneyline: +190)
• 6/29/2024: 11-3 CHW (Favorite: White Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/20/2023: 10-5 CHW (Favorite: White Sox, Spread: -1.5, Total: 11.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 8/19/2023: 11-5 COL (Favorite: White Sox, Spread: -1.5, Total: 11.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/18/2023: 14-1 COL (Favorite: Rockies, Spread: -1.5, Total: 12, Favorite Moneyline: -124, Underdog Moneyline: +106)

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