Western Michigan vs Buffalo Prediction, Odds, Picks, Best Bets for Week 5 2026

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The Western Michigan Broncos are among the college football squads busy on Saturday, up against the Buffalo Bulls.

We've got you covered, in terms of the most important info regarding NCAA football betting lines, before you make your wager on FanDuel Sportsbook.

Western Michigan vs Buffalo Odds & Spread

All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
Moneyline: Western Michigan: (-549) | Buffalo: (+400)
Spread: Western Michigan: -12.5 (-110) | Buffalo: +12.5 (-110)
Total: 46.5 -- Over: (-105) | Under: (-115)

Western Michigan has two wins against the spread this year.
Western Michigan has covered every time (1-0) as a 12.5-point favorite or greater this season.
Western Michigan has had two games (out of four) hit the over this year.
Buffalo has not won a game against the spread this year.
Buffalo has no wins ATS (0-1) as a 12.5-point underdog or more this season.
Buffalo has played four games this season, and three of them have gone over the total.

All college football win probability predictions and picks are according to numberFire.
Prediction: Broncos win (80.7%)

Western Michigan is favored by 12.5 points versus Buffalo. Western Michigan is -110 to cover the spread, while Buffalo is -110.

An over/under of 46.5 has been set for Western Michigan-Buffalo on Oct. 3, with the over being -105 and the under -115.

Western Michigan is the favorite, -549 on the moneyline, while Buffalo is a +400 underdog.

	Point Scored (PG)	Points Scored CFB Rank	Points Allowed (PG)	Points Allowed CFB Rank	Average Total	Total Games
Western Michigan	24.0	98	20.0	45	49.5	4
Buffalo	21.3	118	33.3	123	47.5	4

Check out even more in-depth Western Michigan vs. Buffalo analysis on FanDuel Research.

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