Vanderbilt vs LSU College Basketball Prediction, Odds, Picks, Best Bets for Jan. 10

The Vanderbilt Commodores (15-0, 2-0 SEC) will host the LSU Tigers (12-3, 0-2 SEC) after winning nine straight home games.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Vanderbilt vs. LSU Game Info and Odds

• Game day: Saturday, January 10, 2026
• Game time: 1 p.m. ET
• TV channel: SEC Network
• Location: Nashville, Tennessee
• Arena: Memorial Gymnasium

Vanderbilt vs. LSU Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Vanderbilt win (85.3%)

Before you wager on Saturday's Vanderbilt-LSU spread (Vanderbilt -15.5) or over/under (162.5 points), check out the betting insights and trends below.

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Vanderbilt vs. LSU: ATS Betting Stats and Trends

• Vanderbilt has covered 10 times in 15 matchups with a spread this season.
• LSU is 8-7-0 ATS this year.
• The Commodores have done a better job covering the spread in road games (3-1-0) than they have at home (5-3-0).
• The Tigers' winning percentage against the spread at home last season was .500 (9-9-0). On the road, it was .400 (4-6-0).

Vanderbilt vs. LSU: Moneyline Betting Stats

• Vanderbilt has yet to lose any of the 11 games it has been chosen as the moneyline favorite in this season.
• The Commodores have yet to lose in three games when named as moneyline favorite of -2000 or better.
• LSU has been the moneyline underdog just two other times so far this season, and it lost both games.
• The Tigers have yet to play as a moneyline underdog of +980 or longer.
• Oddsmakers have implied with the moneyline set for this matchup that Vanderbilt has a 95.2% chance of pulling out a win.

Vanderbilt vs. LSU Head-to-Head Comparison

• Vanderbilt was 55th in the nation in points scored (78.9 per game) and 249th in points allowed (74.3) last season.
• Vanderbilt grabbed 31.2 rebounds per game and gave up 31.9 boards last season, ranking 221st and 226th, respectively, in the country.
• At 13.8 assists per game last season, Vanderbilt was 158th in the country.
• Vanderbilt was 40th in the nation in turnovers per game (9.6) and 40th in turnovers forced (13.4) last year.
• With 73.8 points per game on offense, LSU ranked 179th in college basketball last year. At the other end of the court, it allowed 73.6 points per contest, which ranked 228th in college basketball.
• LSU ranked 156th in the country with 32.4 boards per contest, but it allowed 34.4 rebounds per game, which ranked 21st-worst in college basketball.
• LSU ranked 241st in the country with 12.8 dimes per game.
• LSU averaged 12.3 turnovers per game (288th-ranked in college basketball). It forced 11.2 turnovers per contest (184th-ranked).

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