Vanderbilt vs LSU College Basketball Prediction, Odds, Picks, Best Bets for Jan. 10

The Vanderbilt Commodores (15-0, 2-0 SEC) will look to continue a 15-game winning streak when they host the LSU Tigers (12-3, 0-2 SEC) on January 10, 2026 at Memorial Gymnasium.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Vanderbilt vs. LSU Game Info and Odds

• Game day: Saturday, January 10, 2026
• Game time: 1 p.m. ET
• TV channel: SEC Network
• Location: Nashville, Tennessee
• Arena: Memorial Gymnasium

Vanderbilt vs. LSU Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Vanderbilt win (85.5%)

Before making a bet on Saturday's Vanderbilt-LSU spread (Vanderbilt -14.5) or over/under (162.5 points), check out the betting insights and trends below.

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Vanderbilt vs. LSU: ATS Betting Stats and Trends

• Vanderbilt has covered 10 times in 15 matchups with a spread this season.
• LSU is 8-7-0 ATS this season.
• The Commodores have a worse record against the spread in home games (5-3-0) than they do in road games (3-1-0).
• Against the spread, the Tigers were better at home (9-9-0) than on the road (4-6-0) last season.

Vanderbilt vs. LSU: Moneyline Betting Stats

• Vanderbilt has been named as the moneyline favorite 11 times this year and has yet to lose any of those games.
• The Commodores have yet to lose in three games when named as moneyline favorite of -1695 or better.
• LSU has been the moneyline underdog only two other times so far this season, and it lost both games.
• The Tigers have not yet played as a moneyline underdog of +890 or longer.
• Vanderbilt has an implied victory probability of 94.4% according to the moneyline set for this matchup.

Vanderbilt vs. LSU Head-to-Head Comparison

• Vanderbilt is outscoring opponents by 21.6 points per game with a +324 scoring differential overall. It puts up 93.6 points per game (seventh in college basketball) and gives up 72.0 per outing (144th in college basketball).
• Duke Miles leads Vanderbilt, putting up 17.2 points per game (111th in college basketball).
• LSU's +221 scoring differential (outscoring opponents by 14.8 points per game) is a result of putting up 86.5 points per game (38th in college basketball) while allowing 71.7 per outing (142nd in college basketball).
• Dedan Thomas Jr.'s team-leading 16.2 points per game rank him 178th in the nation.
• The Commodores come out on top in the rebound battle by an average of 6.5 boards. They are pulling down 35.4 rebounds per game (75th in college basketball) compared to their opponents' 28.9 per contest.
• Devin tops the team with 7.3 rebounds per game (129th in college basketball play).
• The Tigers win the rebound battle by an average of 8.6 boards. They are recording 37.6 rebounds per game (29th in college basketball) compared to their opponents' 29.0.
• Marquel Sutton's 8.9 rebounds per game lead the Tigers and rank 39th in the country.
• Vanderbilt ranks third in college basketball with 113.8 points scored per 100 possessions, and 66th in college basketball defensively with 87.5 points conceded per 100 possessions.
• The Tigers rank 22nd in college basketball with 108.6 points scored per 100 possessions, and 114th defensively with 90.1 points conceded per 100 possessions.

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