Tigers vs Pirates Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 25

Odds updated as of 1:11 a.m.

Friday's slate in the MLB includes a matchup between the Detroit Tigers and the Pittsburgh Pirates.

All the info you need to make smart wagers on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Tigers vs Pirates Game Info

• Detroit Tigers (74-85) vs. Pittsburgh Pirates (81-78)
• Date: Friday, September 25, 2026
• Time: 6:40 p.m. ET
• Venue: Comerica Park -- Detroit, Michigan
• Coverage: DSN and SportsNet PT

Tigers vs Pirates Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: DET: (-108) | PIT: (-108)
• Spread: DET: +1.5 (-194) | PIT: -1.5 (+160)
• Total: 7.5 -- Over: (-138) | Under: (+112)

Tigers vs Pirates Probable Starting Pitchers

Probable Pitchers: Jackson Jobe (Tigers) - 2-3, 3.98 ERA vs Bubba Chandler (Pirates) - 8-9, 4.34 ERA

This contest's pitching matchup is set, as the Tigers will send Jackson Jobe (2-3) to the mound, while Bubba Chandler (8-9) will take the ball for the Pirates. Jobe and his team have a record of 5-3-0 against the spread when he starts. Jobe's team is 2-1 this season when he starts and they are the moneyline favorite. The Pirates have gone 17-12-0 against the spread when Chandler starts. The Pirates have an 8-10 record in Chandler's 18 starts this season when they were the moneyline underdog.

Tigers vs Pirates Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Tigers win (51.6%)

Tigers vs Pirates Moneyline

• Detroit is the favorite, -108 on the moneyline, while Pittsburgh is a -108 underdog on the road.

Tigers vs Pirates Spread

Tigers vs Pirates Over/Under

• A combined run total of 7.5 has been set for Tigers-Pirates on Sept. 25, with the over at -138 and the under at +112.

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Tigers vs Pirates Betting Trends

• The Tigers have come away with 43 wins in the 80 contests they have been listed as the favorites in this season.
• This year Detroit has won 42 of 84 games when listed as at least -108 on the moneyline.
• The Tigers and their opponents have gone over in 67 of their 153 games with a total set by sportsbooks this season.
• The Tigers have an against the spread mark of 78-75-0 in 153 games with a line this season.
• The Pirates are 32-41 in games they were the underdog on the moneyline (winning 43.8% of those games).
• In games it has played as a moneyline underdog with odds of -108 or longer, Pittsburgh has a record of 32-42 (43.2%).
• The Pirates have combined with opponents to hit the over on the total 81 times this season for an 81-72-4 record against the over/under.
• The Pirates have put together a 78-79-0 record ATS this season (covering 49.7% of the time).

Tigers Player Leaders

• Kevin McGonigle leads Detroit OPS (.806) this season. He has a .278 batting average, an on-base percentage of .378, and a slugging percentage of .428.
• Among all qualifying hitters in MLB, he ranks 27th in batting average, 11th in on-base percentage, and 66th in slugging.
• McGonigle hopes to build on a two-game hitting streak in this matchup. During his last five outings he is batting .348 with two doubles, a triple, two walks and five RBIs.
• Riley Greene has 141 hits, which is tops among Detroit batters this season. He's batting .282 with 54 extra-base hits. He's also slugging .478 with an on-base percentage of .371.
• Among all qualifying players, he is 18th in batting average, 14th in on-base percentage and 28th in slugging percentage.
• Dillon Dingler has 132 hits this season and has a slash line of .244/.304/.450.
• Spencer Torkelson is batting .228 with a .328 OBP and 74 RBI for Detroit this season.

Pirates Player Leaders

• Bryan Reynolds has a team-best .365 on-base percentage. He's batting .261 and slugging .422.
• Including all the qualified hitters in the big leagues, his batting average places him 61st, his on-base percentage is 20th, and he is 69th in slugging.
• Brandon Lowe has racked up 151 hits to lead his team. He has a batting average of .262 while slugging .493 with an on-base percentage of .332.
• Including all qualifying players, he ranks 55th in batting average, 67th in on-base percentage and 16th in slugging percentage.
• Nick Gonzales has put up a team-high OBP (.365) and slugging percentage (.388).
• Ryan O'Hearn is batting .265 with 17 doubles, 18 home runs and 35 walks.

Tigers vs Pirates Head to Head

• 8/19/2026: 4-3 PIT (Favorite: Pirates, Spread: -1.5, Total: 8, Favorite Moneyline: -154, Underdog Moneyline: +142)
• 8/18/2026: 4-1 PIT (Favorite: Pirates, Spread: -1.5, Total: 8, Favorite Moneyline: -150, Underdog Moneyline: +140)
• 8/17/2026: 8-5 DET (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -106, Underdog Moneyline: -102)
• 7/23/2025: 6-1 PIT (Favorite: Tigers, Spread: -1.5, Total: 9, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 7/22/2025: 8-5 PIT (Favorite: Tigers, Spread: -1.5, Total: 8, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 7/21/2025: 3-0 PIT (Favorite: Pirates, Spread: -1.5, Total: 7, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/19/2025: 8-4 PIT (Favorite: Pirates, Spread: -1.5, Total: 7, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/17/2025: 7-3 DET (Favorite: Tigers, Spread: -1.5, Total: 8, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 5/29/2024: 10-2 PIT (Favorite: Pirates, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 5/29/2024: 8-0 DET (Favorite: Tigers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -146, Underdog Moneyline: +124)

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