Tigers vs Pirates Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 25

Odds updated as of 6:12 p.m.

The Detroit Tigers are among the MLB squads busy on Friday, up against the Pittsburgh Pirates.

We've got you covered, in terms of the vital info regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Tigers vs Pirates Game Info

• Detroit Tigers (74-85) vs. Pittsburgh Pirates (81-78)
• Date: Friday, September 25, 2026
• Time: 6:40 p.m. ET
• Venue: Comerica Park -- Detroit, Michigan
• Coverage: DSN and SportsNet PT

Tigers vs Pirates Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: DET: (-118) | PIT: (+100)
• Spread: DET: -1.5 (+168) | PIT: +1.5 (-205)
• Total: 7.5 -- Over: (-128) | Under: (+104)

Tigers vs Pirates Probable Starting Pitchers

Probable Pitchers: Jackson Jobe (Tigers) - 2-3, 3.98 ERA vs Bubba Chandler (Pirates) - 8-9, 4.34 ERA

The Tigers will call on Jackson Jobe (2-3) versus the Pirates and Bubba Chandler (8-9). When Jobe starts, his team is 5-3-0 against the spread this season. Jobe's team has a record of 2-1 this season when he starts and they are the favorite on the moneyline. The Pirates are 17-12-0 ATS in Chandler's 29 starts that had a set spread. The Pirates are 8-10 in Chandler's 18 starts this season that they were the moneyline underdog.

Tigers vs Pirates Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Tigers win (51.7%)

Tigers vs Pirates Moneyline

• The moneyline numbers for Tigers vs. Pirates reveal Detroit as the favorite (-118) and Pittsburgh as the underdog (+100) on the road.

Tigers vs Pirates Spread

• The Tigers are 1.5-run home favorites on the runline against the Pirates. The Tigers are +168 to cover, and the Pirates are -205.

Tigers vs Pirates Over/Under

• The over/under for Tigers-Pirates on Sept. 25 is 7.5. The over is -128, and the under is +104.

Bet on Detroit Tigers vs. Pittsburgh Pirates on FanDuel today!

Tigers vs Pirates Betting Trends

• The Tigers have been victorious in 43, or 53.8%, of the 80 contests they have been chosen as favorites in this season.
• This season Detroit has been victorious 36 times in 65 chances when named as a favorite of at least -118 on the moneyline.
• The Tigers' games have gone over the total in 67 of their 153 opportunities.
• The Tigers are 78-75-0 against the spread in their 153 games with a line set by sportsbooks this season.
• The Pirates have gone 32-41 in games they were the underdog on the moneyline (winning 43.8% of those games).
• When it has played as a moneyline underdog with odds of +100 or longer, Pittsburgh has a 24-33 record (winning 42.1% of its games).
• The Pirates have combined with opponents to hit the over on the total 81 times this season for an 81-72-4 record against the over/under.
• The Pirates have gone 78-79-0 against the spread this season.

Tigers Player Leaders

• Kevin McGonigle leads Detroit OPS (.806) this season. He has a .278 batting average, an on-base percentage of .378, and a slugging percentage of .428.
• Among all qualified hitters in MLB, his batting average ranks 27th, his on-base percentage ranks 11th, and he is 65th in slugging.
• McGonigle will look for his third straight game with a hit in this matchup. In his last five games he is batting .348 with two doubles, a triple, two walks and five RBIs.
• Riley Greene leads Detroit with 141 hits. He is batting .282 this season and has 54 extra-base hits. He's also slugging .478 with an on-base percentage of .371.
• His batting average ranks 18th among qualified players, his on-base percentage 14th, and his slugging percentage 27th.
• Dillon Dingler has 132 hits this season and has a slash line of .244/.304/.450.
• Spencer Torkelson has 25 home runs, 74 RBI and a batting average of .228 this season.

Pirates Player Leaders

• Bryan Reynolds a has .365 on-base percentage to lead the Pirates. He's batting .261 while slugging .422.
• Including all qualifying hitters in MLB, he is 59th in batting average, 20th in on-base percentage and 69th in slugging percentage.
• Brandon Lowe's 151 hits lead his team. He has a batting average of .262 while slugging .493 with an on-base percentage of .332.
• He is currently 54th in batting average, 65th in on-base percentage and 16th in slugging percentage among all qualifying hitters.
• Nick Gonzales has put up a team-high OBP (.365) and slugging percentage (.388).
• Ryan O'Hearn is hitting .265 with 17 doubles, 18 home runs and 35 walks.

Tigers vs Pirates Head to Head

• 8/19/2026: 4-3 PIT (Favorite: Pirates, Spread: -1.5, Total: 8, Favorite Moneyline: -154, Underdog Moneyline: +142)
• 8/18/2026: 4-1 PIT (Favorite: Pirates, Spread: -1.5, Total: 8, Favorite Moneyline: -150, Underdog Moneyline: +140)
• 8/17/2026: 8-5 DET (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -106, Underdog Moneyline: -102)
• 7/23/2025: 6-1 PIT (Favorite: Tigers, Spread: -1.5, Total: 9, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 7/22/2025: 8-5 PIT (Favorite: Tigers, Spread: -1.5, Total: 8, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 7/21/2025: 3-0 PIT (Favorite: Pirates, Spread: -1.5, Total: 7, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/19/2025: 8-4 PIT (Favorite: Pirates, Spread: -1.5, Total: 7, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/17/2025: 7-3 DET (Favorite: Tigers, Spread: -1.5, Total: 8, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 5/29/2024: 10-2 PIT (Favorite: Pirates, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 5/29/2024: 8-0 DET (Favorite: Tigers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -146, Underdog Moneyline: +124)

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