Tigers vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for AL Wild Card Game 1 on Sept. 30

Odds updated as of 8:11 p.m.

The Detroit Tigers versus the Cleveland Guardians in Game 1 of the AL Wild Card Series is on the MLB schedule for Tuesday.

All the info you need to make smart wagers on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Tigers vs Guardians Game Info

• Detroit Tigers (87-75) vs. Cleveland Guardians (88-74)
• Date: Tuesday, September 30, 2025
• Time: 1:08 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: ESPN

Tigers vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: DET: (-164) | CLE: (+138)
• Spread: DET: -1.5 (+118) | CLE: +1.5 (-142)
• Total: 6.5 -- Over: (+102) | Under: (-124)

Tigers vs Guardians Probable Starting Pitchers

Probable Pitchers: Tarik Skubal (Tigers) - 13-6, 2.21 ERA vs Gavin Williams (Guardians) - 12-5, 3.06 ERA

The probable starters are Tarik Skubal (13-6, 2.21 ERA) for the Tigers and Gavin Williams (12-5, 3.06 ERA) for the Guardians. Skubal's team is 13-16-0 against the spread this season in his starts. Skubal's team has won 66.7% of his starts when they are favored on the moneyline (18-9). The Guardians have a 15-16-0 ATS record in Williams' 31 starts with a set spread. The Guardians have been the moneyline underdog in 20 of Williams' starts this season, and they went 10-10 in those matchups.

Tigers vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Tigers win (64.4%)

Tigers vs Guardians Moneyline

• The Tigers vs Guardians moneyline has Detroit as a -164 favorite, while Cleveland is a +138 underdog at home.

Tigers vs Guardians Spread

• The Tigers are favored by 1.5 runs on the road against the Guardians. The Tigers are +118 to cover the spread, while the Guardians are -142.

Tigers vs Guardians Over/Under

• Tigers versus Guardians on Sept. 30 has an over/under of 6.5 runs, with the odds on the over +102 and the under set at -124.

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Tigers vs Guardians Betting Trends

• The Tigers have come away with 58 wins in the 105 contests they have been listed as the favorites in this season.
• This season Detroit has been victorious 27 times in 44 chances when named as a favorite of at least -164 on the moneyline.
• The Tigers and their opponents have gone over the total this season in 78 of their 155 opportunities.
• The Tigers are 71-84-0 against the spread in their 155 games that had a posted line this season.
• The Guardians have been the moneyline underdog 87 total times this season. They've gone 41-46 in those games.
• Cleveland is 8-15 (winning just 34.8% of its games) when playing as a moneyline underdog of +138 or longer.
• The Guardians have played in 158 games with an over/under set, and have combined with opponents to go over the total 68 times (68-84-6).
• The Guardians have an 85-73-0 record ATS this season.

Tigers Player Leaders

• Gleyber Torres leads Detroit in OBP (.358) this season, fueled by 136 hits. He has a .256 batting average and a slugging percentage of .387.
• Among qualified hitters in MLB, his batting average ranks 77th, his on-base percentage ranks 23rd, and he is 118th in slugging.
• Riley Greene leads Detroit with 155 hits and a team-best slugging percentage of .493. He's batting .258 with an on-base percentage of .313.
• Among all qualifying players, he ranks 69th in batting average, 104th in on-base percentage and 21st in slugging percentage.
• Spencer Torkelson has 135 hits this season and has a slash line of .240/.333/.456.
• Zach McKinstry is batting .259 with a .333 OBP and 49 RBI for Detroit this season.

Guardians Player Leaders

• Jose Ramirez has 168 hits with a .360 on-base percentage, leading the Guardians in both categories. He's batting .283 and slugging .503.
• Including all the qualifying hitters in the big leagues, he is 21st in batting average, 19th in on-base percentage and 16th in slugging percentage.
• Steven Kwan is slugging .374 to pace his team. He has a batting average of .272 with an on-base percentage of .330.
• He is 36th in batting average, 72nd in on-base percentage and 129th in slugging percentage in the majors.
• Kyle Manzardo has 19 doubles, two triples, 27 home runs and 48 walks while hitting .234.
• Angel Martinez has 23 doubles, two triples, 11 home runs and 23 walks while hitting .224.

Tigers vs Guardians Head to Head

• 9/25/2025: 4-2 DET (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 9/23/2025: 5-2 CLE (Favorite: Tigers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 9/18/2025: 3-1 CLE (Favorite: Tigers, Spread: -1.5, Total: 7, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 9/17/2025: 4-0 CLE (Favorite: Tigers, Spread: -1.5, Total: 8, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 9/16/2025: 7-5 CLE (Favorite: Tigers, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/6/2025: 7-2 DET (Favorite: Tigers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 7/5/2025: 1-0 DET (Favorite: Tigers, Spread: -1.5, Total: 9, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/4/2025: 2-1 DET (Favorite: Tigers, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 5/25/2025: 5-0 DET (Favorite: Tigers, Spread: -1.5, Total: 7, Favorite Moneyline: -290, Underdog Moneyline: +235)
• 5/24/2025: 7-5 CLE (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)

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