TCU vs Iowa State Prediction, Odds, Picks, Best Bets for Week 11 2025

In college football action on Saturday, the TCU Horned Frogs play the Iowa State Cyclones.

Get the latest NCAA football odds ahead of this matchup on FanDuel Sportsbook.

TCU vs Iowa State Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TCU: (-275) | Iowa State: (+225)
• Spread: TCU: -7.5 (-105) | Iowa State: +7.5 (-115)
• Total: 57.5 -- Over: (-115) | Under: (-105)

TCU vs Iowa State Betting Trends

• TCU is 4-4-0 against the spread this season.
• TCU has won once ATS (1-2) as a 7.5-point or higher favorite this season.
• This year, four of TCU's eight games have hit the over.
• Iowa State has beaten the spread three times in nine games.
• Iowa State has played nine games this season, and four of them have hit the over.

TCU vs Iowa State Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Horned Frogs win (57.7%)

TCU vs Iowa State Point Spread

Iowa State is listed as an underdog by 7.5 points (-115 odds), and TCU, the favorite, is -105 to cover.

TCU vs Iowa State Over/Under

A combined point total of 57.5 has been set for TCU-Iowa State on Nov. 8, with the over at -115 and the under at -105.

TCU vs Iowa State Moneyline

Looking at the moneyline for TCU-Iowa State, TCU is the favorite at -275, and Iowa State is +225.

TCU vs. Iowa State Points Insights

TCU vs. Iowa State Game Info

• Game day: Saturday, November 8, 2025
• Game time: 3:30 p.m. ET
• TV channel: FOX
• Location: Fort Worth, Texas
• Stadium: Amon G. Carter Stadium

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Check out even more in-depth TCU vs. Iowa State analysis on FanDuel Research.