SMU vs Missouri State Prediction, Odds, Picks, Best Bets for Week 4 2026

The SMU Mustangs will take on the Missouri State Bears in college football action on Saturday.

We've got you covered, in terms of the most important info regarding NCAA football betting lines, before you make your wager on FanDuel Sportsbook.

SMU vs Missouri State Odds & Spread

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SMU: (-10000) | Missouri State: (+3000)
• Spread: SMU: -32.5 (-105) | Missouri State: +32.5 (-115)
• Total: 60.5 -- Over: (-110) | Under: (-110)

SMU vs Missouri State Betting Trends

• SMU hasn won once against the spread this year.
• SMU has had two games (out of three) go over the total this season.
• Missouri State has but one win versus the spread this season.
• Missouri State has no wins ATS (0-1) as a 32.5-point underdog or greater this season.
• Missouri State has played two games (out of three) which finished over the total this year.

SMU vs Missouri State Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Mustangs win (97.4%)

SMU vs Missouri State Point Spread

SMU is a 32.5-point favorite against Missouri State. SMU is -105 to cover the spread, and Missouri State is -115.

SMU vs Missouri State Over/Under

An over/under of 60.5 has been set for SMU-Missouri State on Sept. 26, with the over being -110 and the under -110.

SMU vs Missouri State Moneyline

SMU is the favorite, -10000 on the moneyline, while Missouri State is a +3000 underdog.

SMU vs. Missouri State Points Insights

SMU vs. Missouri State Game Info

• Game day: Saturday, September 26, 2026
• Game time: 9 p.m. ET
• TV channel: ACC Network
• Location: University Park, Texas
• Stadium: Gerald J. Ford Stadium

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

Check out even more in-depth SMU vs. Missouri State analysis on FanDuel Research.