SMU vs Florida State Prediction, Odds, Picks, Best Bets for Week 1 2026

College football's Monday slate includes the SMU Mustangs taking on the Florida State Seminoles.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

SMU vs Florida State Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SMU: (-142) | Florida State: (+118)
• Spread: SMU: -2.5 (-115) | Florida State: +2.5 (-105)
• Total: 54.5 -- Over: (-110) | Under: (-110)

SMU vs Florida State Betting Trends

• SMU had six wins in 12 games against the spread last season.
• SMU went 3-5 as at least 2.5-point favorites last year.
• Last season, four of SMU's 12 games hit the over.
• Florida State posted a 4-7-0 record against the spread last season.
• Florida State had one win ATS (1-1) as underdogs of 2.5 points or greater last season.
• Florida State had five of its 11 games go over the point total last season.

SMU vs Florida State Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Seminoles win (65.2%)

SMU vs Florida State Point Spread

Florida State is listed as an underdog by 2.5 points (-105 odds), and SMU, the favorite, is -115 to cover.

SMU vs Florida State Over/Under

The over/under for SMU-Florida State on Sept. 7 is 54.5. The over is -110, and the under is -110.

SMU vs Florida State Moneyline

Looking at the moneyline for Florida State-SMU, Florida State is the underdog at +118, and SMU is -142.

SMU vs. Florida State Points Insights

• The Mustangs had an average implied point total of 33.1 last season, which is 4.1 points higher than their implied total in Monday's game (29).
• The average implied point total last season for the Seminoles (33.5) is 7.5 more points than the team's implied total in this matchup (26).

SMU vs. Florida State Game Info

• Game day: Monday, September 7, 2026
• Game time: 7:30 p.m. ET
• TV channel: ESPN
• Location: Tallahassee, Florida
• Stadium: Bobby Bowden Field at Doak Campbell Stadium

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Check out even more in-depth SMU vs. Florida State analysis on FanDuel Research.