SMU vs Florida State Prediction, Odds, Picks, Best Bets for Week 1 2026

NCAA football action on Monday includes the SMU Mustangs taking on the Florida State Seminoles.

Get the latest NCAA football odds ahead of this game on FanDuel Sportsbook.

SMU vs Florida State Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SMU: (-150) | Florida State: (+125)
• Spread: SMU: -2.5 (-122) | Florida State: +2.5 (100)
• Total: 53.5 -- Over: (-105) | Under: (-115)

SMU vs Florida State Betting Trends

• SMU's record against the spread last season was 6-6-0.
• As 2.5-point or greater favorites, SMU went 3-5 against the spread last year.
• Out of 12 SMU games last year, four went over the total.
• Florida State posted a 4-7-0 record against the spread last season.
• As a 2.5-point underdog or more, Florida State had one win ATS (1-1) last season.
• There were five Florida State games (out of 11) that hit the over last season.

SMU vs Florida State Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Seminoles win (56.6%)

SMU vs Florida State Point Spread

SMU is favored by 2.5 points over Florida State. SMU is -122 to cover the spread, with Florida State being +100.

SMU vs Florida State Over/Under

The over/under for SMU-Florida State on Sept. 7 is 53.5. The over is -105, and the under is -115.

SMU vs Florida State Moneyline

Florida State is a +125 underdog on the moneyline, while SMU is a -150 favorite.

SMU vs. Florida State Points Insights

• The Mustangs' average implied point total last season was 5.1 more points than their implied total in Monday's game (33.1 implied points on average compared to 28 implied points in this game).
• The average implied point total last season for the Seminoles (33.5) is 7.5 more points than the team's implied total in this matchup (26).

SMU vs. Florida State Game Info

• Game day: Monday, September 7, 2026
• Game time: 7:30 p.m. ET
• TV channel: ESPN
• Location: Tallahassee, Florida
• Stadium: Bobby Bowden Field at Doak Campbell Stadium

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Check out even more in-depth SMU vs. Florida State analysis on FanDuel Research.