Red Sox vs Orioles Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 6

Odds updated as of 9:12 p.m.

The Boston Red Sox are among the MLB squads playing on Sunday, versus the Baltimore Orioles.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital info regarding this matchup.

Red Sox vs Orioles Game Info

• Boston Red Sox (77-65) vs. Baltimore Orioles (69-73)
• Date: Sunday, September 6, 2026
• Time: 1:35 p.m. ET
• Venue: Oriole Park at Camden Yards -- Baltimore, Maryland
• Coverage: MASN and NESN

Red Sox vs Orioles Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BOS: (-136) | BAL: (+116)
• Spread: BOS: -1.5 (+128) | BAL: +1.5 (-154)
• Total: 7.5 -- Over: (-120) | Under: (-102)

Red Sox vs Orioles Probable Starting Pitchers

Probable Pitchers: Payton Tolle (Red Sox) - 8-6, 3.23 ERA vs Kyle Bradish (Orioles) - 7-12, 4.01 ERA

The Red Sox will look to Payton Tolle (8-6) versus the Orioles and Kyle Bradish (7-12). Tolle's team is 9-14-0 against the spread this season in his starts. Tolle's team has a record of 11-5 this season when he starts and they are the favorite on the moneyline. The Orioles have a 12-15-0 record against the spread in Bradish's starts. The Orioles have a 7-5 record in Bradish's 12 starts this season when they were the underdog on the moneyline.

Red Sox vs Orioles Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Red Sox win (57.8%)

Red Sox vs Orioles Moneyline

• Baltimore is a +116 underdog on the moneyline, while Boston is a -136 favorite on the road.

Red Sox vs Orioles Spread

• The Red Sox are at the Orioles and are favored by 1.5 runs (+128 to cover) on the runline. Baltimore is -154 to cover.

Red Sox vs Orioles Over/Under

• The over/under for the Red Sox versus Orioles contest on Sept. 6 has been set at 7.5, with -120 odds on the over and -102 odds on the under.

Bet on Boston Red Sox vs. Baltimore Orioles on FanDuel today!

Red Sox vs Orioles Betting Trends

• The Red Sox have been victorious in 53, or 54.1%, of the 98 contests they have been chosen as favorites in this season.
• This season Boston has been victorious 27 times in 50 chances when named as a favorite of at least -136 on the moneyline.
• The Red Sox and their opponents have hit the over in 66 of their 140 games with a total set by oddsmakers this season.
• The Red Sox are 66-74-0 against the spread in their 140 games with a line set by sportsbooks this season.
• The Orioles have been the underdog on the moneyline 69 total times this season. They've finished 32-37 in those games.
• Baltimore has gone 10-18 when playing as a moneyline underdog with odds of +116 or longer (35.7%).
• The Orioles have played in 141 games with an over/under set, and have combined with opponents to go over the total 71 times (71-66-4).
• The Orioles have collected a 73-68-0 record ATS this season (covering 51.8% of the time).

Red Sox Player Leaders

• Wilyer Abreu is hitting .257 with 34 doubles, four triples, 23 home runs and 64 walks. He has an on-base percentage of .336 while slugging .466.
• Among all qualified hitters in MLB, he ranks 67th in batting average, 61st in on-base percentage, and 35th in slugging.
• Ceddanne Rafaela leads Boston in slugging percentage (.443) thanks to 51 extra-base hits. He's batting .282 with an on-base percentage of .317.
• He is 18th in batting average, 93rd in on-base percentage and 49th in slugging in MLB.
• Caleb Durbin is batting .248 with a .381 slugging percentage and 62 RBI this year.
• Jarren Duran has been key for Boston with 103 hits, an OBP of .260 plus a slugging percentage of .361.

Orioles Player Leaders

• Pete Alonso has racked up a team-best OBP (.358) and slugging percentage (.498), while leading the Orioles in hits (142, while batting .267).
• He ranks 48th in batting average, 31st in on-base percentage and 16th in slugging percentage among all qualifying hitters in the big leagues.
• Gunnar Henderson is hitting .221 with 24 doubles, five triples, 22 home runs and 58 walks. He's slugging .399 with an on-base percentage of .303.
• Including all qualified hitters, he ranks 124th in batting average, 115th in on-base percentage and 92nd in slugging percentage.
• Leody Taveras has 15 doubles, six triples, eight home runs and 40 walks while hitting .217.
• Coby Mayo has 13 doubles, three triples, 19 home runs and 26 walks while batting .222.

Red Sox vs Orioles Head to Head

• 9/4/2026: 1-0 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/3/2026: 6-5 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 7/22/2026: 5-1 BAL (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/22/2026: 6-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 7/20/2026: 6-5 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 6/4/2026: 8-2 BAL (Favorite: Red Sox, Spread: -1.5, Total: 10.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/3/2026: 8-1 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 6/2/2026: 4-2 BAL (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 4/26/2026: 5-3 BOS (Favorite: Orioles, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/25/2026: 17-1 BOS (Favorite: Orioles, Spread: -1.5, Total: 7, Favorite Moneyline: -126, Underdog Moneyline: +108)

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