Red Sox vs Orioles Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 4

Odds updated as of 6:13 p.m.

The Boston Red Sox are among the MLB teams busy on Friday, up against the Baltimore Orioles.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important information about this matchup.

Red Sox vs Orioles Game Info

• Boston Red Sox (76-65) vs. Baltimore Orioles (69-72)
• Date: Friday, September 4, 2026
• Time: 7:05 p.m. ET
• Venue: Oriole Park at Camden Yards -- Baltimore, Maryland
• Coverage: MASN and NESN

Red Sox vs Orioles Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BOS: (-116) | BAL: (-102)
• Spread: BOS: -1.5 (+138) | BAL: +1.5 (-166)
• Total: 8 -- Over: (-114) | Under: (-106)

Red Sox vs Orioles Probable Starting Pitchers

Probable Pitchers: Ranger Suarez (Red Sox) - 5-4, 3.64 ERA vs Shane Baz (Orioles) - 5-14, 4.01 ERA

The Red Sox will give the nod to Ranger Suarez (5-4, 3.64 ERA), who is eyeing win No. 6 on the season, and the Orioles will counter with Shane Baz (5-14, 4.01 ERA). Suarez's team is 13-11-0 against the spread this season in his starts. Suarez's team is 10-8 this season when he starts and they are the moneyline favorite. The Orioles have gone 11-15-0 against the spread when Baz starts. The Orioles have a 2-12 record in Baz's 14 starts this season when they were the underdog on the moneyline.

Red Sox vs Orioles Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Red Sox win (59%)

Red Sox vs Orioles Moneyline

• Boston is a -116 favorite on the moneyline, while Baltimore is a -102 underdog at home.

Red Sox vs Orioles Spread

• The Orioles are +1.5 on the spread (-166 to cover), and Boston is +138 to cover the runline.

Red Sox vs Orioles Over/Under

• A total of 8 runs has been set for the Red Sox-Orioles game on Sept. 4, with the over available at -114 and the under at -106.

Bet on Boston Red Sox vs. Baltimore Orioles on FanDuel today!

Red Sox vs Orioles Betting Trends

• The Red Sox have been favorites in 97 games this season and have come away with the win 52 times (53.6%) in those contests.
• This season Boston has been victorious 49 times in 91 chances when named as a favorite of at least -116 on the moneyline.
• The Red Sox and their opponents have gone over the total this season in 66 of their 139 opportunities.
• The Red Sox have an against the spread mark of 66-73-0 in 139 games with a line this season.
• The Orioles have been the underdog on the moneyline 68 total times this season. They've gone 32-36 in those games.
• Baltimore has a record of 26-31 when it has played as a moneyline underdog with odds of -102 or longer (45.6%).
• In the 140 games bookmakers have set an over/under for the Orioles, they have combined with opponents to go over the total 71 times (71-65-4).
• The Orioles have put together a 72-68-0 record against the spread this season (covering 51.4% of the time).

Red Sox Player Leaders

• Wilyer Abreu is batting .258 with 34 doubles, four triples, 23 home runs and 62 walks. He has an on-base percentage of .335 and a slugging percentage of .468.
• He ranks 64th in batting average, 63rd in on-base percentage, and 33rd in slugging among qualified hitters in baseball.
• Ceddanne Rafaela has hit 16 homers this season while driving in 70 runs. He's batting .282 this season and slugging .443 with an on-base percentage of .317.
• His batting average is 21st among qualified players, his on-base percentage 93rd, and his slugging percentage 50th.
• Caleb Durbin has collected 112 base hits, an OBP of .327 and a slugging percentage of .384 this season.
• Jarren Duran has been key for Boston with 102 hits, an OBP of .260 plus a slugging percentage of .362.

Orioles Player Leaders

• Pete Alonso has racked up a team-best OBP (.360) and slugging percentage (.502), while pacing the Orioles in hits (142, while batting .269).
• Including all the qualifying hitters in the majors, his batting average puts him 45th, his on-base percentage is 27th, and he is 15th in slugging.
• Alonso hopes to build on a three-game hitting streak in this matchup. During his last five outings he is hitting .267 with a home run, four walks and three RBIs.
• Gunnar Henderson has 24 doubles, five triples, 22 home runs and 58 walks while batting .220. He's slugging .400 with an on-base percentage of .303.
• Including all qualifying hitters, he ranks 125th in batting average, 116th in on-base percentage and 93rd in slugging percentage.
• Leody Taveras has 15 doubles, six triples, eight home runs and 40 walks while batting .219.
• Coby Mayo has 13 doubles, three triples, 19 home runs and 26 walks while batting .221.

Red Sox vs Orioles Head to Head

• 9/3/2026: 6-5 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 7/22/2026: 5-1 BAL (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/22/2026: 6-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 7/20/2026: 6-5 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 6/4/2026: 8-2 BAL (Favorite: Red Sox, Spread: -1.5, Total: 10.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/3/2026: 8-1 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 6/2/2026: 4-2 BAL (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 4/26/2026: 5-3 BOS (Favorite: Orioles, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/25/2026: 17-1 BOS (Favorite: Orioles, Spread: -1.5, Total: 7, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 4/24/2026: 10-3 BAL (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!