Rays vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for ALCS Game 4 on Oct. 17

Odds updated as of 7:11 a.m.

The Saturday slate in the MLB includes a matchup between the Tampa Bay Rays and the Cleveland Guardians in Game 4 of the ALCS.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Rays vs Guardians Game Info

• Tampa Bay Rays (98-64) vs. Cleveland Guardians (85-77)
• Date: Saturday, October 17, 2026
• Time: 8 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: TBS, truTV, and HBO Max

Rays vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TB: (-112) | CLE: (-104)
• Spread: TB: -1.5 (+160) | CLE: +1.5 (-194)
• Total: 6.5 -- Over: (-110) | Under: (-110)

Rays vs Guardians Probable Starting Pitchers

Probable Pitchers: Nick Martínez (Rays) - 15-6, 3.10 ERA vs Shawn Armstrong (Guardians) - 2-1, 4.58 ERA

The probable starters are Nick Martinez (15-6, 3.10 ERA) for the Rays and Shawn Armstrong (2-1, 4.58 ERA) for the Guardians. Martinez and his team have a record of 20-12-0 against the spread when he starts. Martinez's team has won 73.3% of his starts when they are favored on the moneyline (11-4). Last season Armstrong and his team went 1-1-0 against the spread in games he pitched. Armstrong and his team were underdogs on the moneyline each game he pitched a season ago.

Rays vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Rays win (56.5%)

Rays vs Guardians Moneyline

• Tampa Bay is a -112 favorite on the moneyline, while Cleveland is a -104 underdog at home.

Rays vs Guardians Spread

• The Guardians are +1.5 on the run line against the Rays. The Guardians are -194 to cover, and the Rays are +160.

Rays vs Guardians Over/Under

• An over/under of 6.5 has been set for Rays-Guardians on Oct. 17, with the over being -110 and the under -110.

Bet on Tampa Bay Rays vs. Cleveland Guardians on FanDuel today!

Rays vs Guardians Betting Trends

• The Rays have won in 68, or 63.6%, of the 107 contests they have been named as odds-on favorites in this year.
• This year Tampa Bay has won 67 of 104 games when listed as at least -112 on the moneyline.
• The Rays and their opponents have hit the over in 77 of their 165 games with a total set by oddsmakers this season.
• The Rays have posted a record of 88-77-0 against the spread this season.
• The Guardians have won 32 of the 62 games they were the moneyline underdog this season (51.6%).
• Cleveland has a 31-27 record (winning 53.4% of its games) when it has played as a moneyline underdog of -104 or longer.
• The Guardians have played in 160 games with an over/under set, and have combined with opponents to go over the total 78 times (78-82-0).
• The Guardians have a 77-83-0 record ATS this season (covering 48.1% of the time).

Rays Player Leaders

• Junior Caminero leads Tampa Bay in total hits (170) this season while batting .276 with 68 extra-base hits. He has an on-base percentage of .360 and a slugging percentage of .524.
• Among all qualified hitters, he ranks 33rd in batting average, his on-base percentage ranks 30th, and he is sixth in slugging.
• Yandy Diaz has hit 22 homers this season while driving in 85 runs. He's batting .293 this season and slugging .446 with an on-base percentage of .359.
• Among qualifiers, he ranks 10th in batting average, 33rd in on-base percentage and 50th in slugging percentage.
• Liam Hicks leads Tampa Bay with an OBP of .367 this season while batting .284 with 56 walks and 66 runs scored.
• Chandler Simpson has no home runs, but 38 RBI and a batting average of .306 this season.
• Simpson brings a two-game hitting streak into this game. During his last five outings he is hitting .200 with a triple and three RBIs.

Guardians Player Leaders

• Chase DeLauter has put up 142 hits, a team-high for the Guardians. He's batting .287 and slugging .457 with an on-base percentage of .363.
• He is 16th in batting average, 24th in on-base percentage and 43rd in slugging percentage among all qualifying hitters in MLB.
• Steven Kwan's .382 OBP and .349 slugging percentage both pace his team. He has a batting average of .282.
• Including all qualified players, he is 21st in batting average, seventh in on-base percentage and 131st in slugging percentage.
• Jose Ramirez is batting .235 with 27 doubles, 12 home runs and 60 walks.
• Brayan Rocchio is hitting .253 with 25 doubles, two triples, 15 home runs and 38 walks.

Rays vs Guardians Head to Head

• 10/15/2026: 3-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 6.5, Favorite Moneyline: -126, Underdog Moneyline: +112)
• 10/13/2026: 3-1 TB (Favorite: Rays, Spread: -1.5, Total: 6.5, Favorite Moneyline: -128, Underdog Moneyline: +114)
• 10/12/2026: 7-3 CLE (Favorite: Rays, Spread: -1.5, Total: 6.5, Favorite Moneyline: -166, Underdog Moneyline: +148)
• 7/26/2026: 1-0 TB (Favorite: Rays, Spread: -1.5, Total: 7, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/25/2026: 3-0 TB (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 7/24/2026: 11-3 TB (Favorite: Rays, Spread: -1.5, Total: 7.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 4/28/2026: 1-0 TB (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 4/27/2026: 3-2 TB (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 9/7/2025: 2-1 CLE (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 9/6/2025: 3-2 CLE (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)

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