Rams vs Eagles Prediction, Odds, Picks, Best Bets for NFL Week 4

In NFL action on Sunday, the Los Angeles Rams face the Philadelphia Eagles.

All the info you need is below, in order to make a smart bet on this matchup at FanDuel Sportsbook.

Rams vs Eagles Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction: Rams win (56.1%)

Rams vs Eagles Point Spread

The Rams are 3-point favorites against the Eagles. The Rams are -110 to cover the spread, while the Eagles are -110 to cover as a 3-point underdog.

Rams vs Eagles Over/Under

Rams versus Eagles on Oct. 4 has an over/under of 43.5 points, with the over -112 and the under -108.

Rams vs Eagles Moneyline

Los Angeles is a -158 favorite on the moneyline, while Philadelphia is a +134 underdog at home.

Rams vs Eagles Betting Trends

• Los Angeles has one win against the spread this year.
• The Rams have one win ATS (1-1) as a 3-point favorite or greater this season.
• The Rams have had one game (out of three) go over the total this season.
• The Eagles have no wins against the spread this year.
• Two of the Eagles' three games in 2026 have hit the over.

Check out even more in-depth Rams vs. Eagles analysis on FanDuel Research.

Rams vs Eagles Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAR: (-158) | PHI: (+134)
• Spread: LAR: -3 (-110) | PHI: +3 (-110)
• Total: 43.5 -- Over: (-112) | Under: (-108)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!