Rams vs Bills Prediction, Odds, Picks, Best Bets for NFL Week 5 Monday Night Football

The Los Angeles Rams are among the NFL teams playing on Monday, versus the Buffalo Bills.

We've got you covered, in terms of the most important info regarding NFL betting lines, before you make your wager on FanDuel Sportsbook.

Rams vs Bills Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction: Rams win (60.2%)

Rams vs Bills Point Spread

The Rams are 3.5-point favorites against the Bills. The Rams are -104 to cover the spread, while the Bills are -118 to cover as a 3.5-point underdog.

Rams vs Bills Over/Under

A total of 54.5 points has been set for the Rams-Bills matchup on Oct. 12, with the over available at -110 and the under at -110.

Rams vs Bills Moneyline

The Rams vs Bills moneyline has Los Angeles as a -176 favorite, while Buffalo is a +148 underdog on the road.

Rams vs Bills Betting Trends

• Los Angeles has posted two wins against the spread this year.
• The Rams have two wins ATS (2-1) as a 3.5-point favorite or greater this year.
• Los Angeles has had two games (out of four) hit the over this year.
• The Bills' record against the spread is 3-1-0.
• The Bills have played four games this season, and three of them have hit the over.

Check out even more in-depth Rams vs. Bills analysis on FanDuel Research.

Rams vs Bills Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAR: (-176) | BUF: (+148)
• Spread: LAR: -3.5 (-104) | BUF: +3.5 (-118)
• Total: 54.5 -- Over: (-110) | Under: (-110)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!