Rams vs 49ers Prediction, Odds, Picks, Best Bets for NFL Week 1 Thursday Night Football

The NFL's Thursday schedule includes the Los Angeles Rams taking on the San Francisco 49ers.

We've got you covered, in terms of the most important info regarding NFL betting lines, before you make your wager on FanDuel Sportsbook.

Rams vs 49ers Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction:

Rams vs 49ers Point Spread

The Rams are 3.5-point favorites against the 49ers. The Rams are -112 to cover the spread, while the 49ers are -108 to cover as a 3.5-point underdog.

Rams vs 49ers Over/Under

The over/under for Rams-49ers on Sept. 10 is 47.5. The over is -114, and the under is -106.

Rams vs 49ers Moneyline

San Francisco is a +166 underdog on the moneyline, while Los Angeles is a -198 favorite on the road.

Rams vs 49ers Betting Trends

• The Rams were 12-5-0 against the spread last year.
• The Rams had an ATS record of 3-1 as 3.5-point favorites or greater last season.
• Last year, 10 of Los Angeles' 17 games hit the over.
• The 49ers posted a 11-6-0 record against the spread last year.
• San Francisco went unbeaten ATS (1-0) as underdogs of 3.5 points or more last season.
• Last season, 10 of the 49ers' 17 games went over the point total.

Check out even more in-depth Rams vs. 49ers analysis on FanDuel Research.

Rams vs 49ers Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAR: (-198) | SF: (+166)
• Spread: LAR: -3.5 (-112) | SF: +3.5 (-108)
• Total: 47.5 -- Over: (-114) | Under: (-106)

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