Pirates vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 1

Odds updated as of 6:12 p.m.

The Pittsburgh Pirates versus the San Francisco Giants is on the MLB schedule for Tuesday.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Pirates vs Giants Game Info

• Pittsburgh Pirates (67-71) vs. San Francisco Giants (57-81)
• Date: Tuesday, September 1, 2026
• Time: 6:40 p.m. ET
• Venue: PNC Park -- Pittsburgh, Pennsylvania
• Coverage: SportsNet PT and NBCS-BA

Pirates vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PIT: (-168) | SF: (+142)
• Spread: PIT: -1.5 (+134) | SF: +1.5 (-162)
• Total: 7.5 -- Over: (-108) | Under: (-112)

Pirates vs Giants Probable Starting Pitchers

Probable Pitchers: Paul Skenes (Pirates) - 9-11, 3.79 ERA vs Logan Webb (Giants) - 8-8, 3.72 ERA

This contest's pitching matchup is set, as the Pirates will send Paul Skenes (9-11) to the mound, while Logan Webb (8-8) will answer the bell for the Giants. Skenes and his team are 9-18-0 ATS this season when he starts. Skenes' team has been victorious in 40.9% of the games he's started as the moneyline favorite with a record of 9-13. The Giants have gone 11-13-0 ATS in Webb's 24 starts with a set spread. The Giants have a 2-7 record in Webb's nine starts this season when they were the underdog on the moneyline.

Pirates vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Pirates win (62.4%)

Pirates vs Giants Moneyline

• Pittsburgh is the favorite, -168 on the moneyline, while San Francisco is a +142 underdog on the road.

Pirates vs Giants Spread

• The Pirates are hosting the Giants and are favored by 1.5 runs on the spread. The Pirates are +134 to cover the runline, with the Giants being -162.

Pirates vs Giants Over/Under

• Pirates versus Giants, on Sept. 1, has an over/under of 7.5, with the over being -108 and the under -112.

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Pirates vs Giants Betting Trends

• The Pirates have been chosen as favorites in 70 games this year and have walked away with the win 39 times (55.7%) in those games.
• This season Pittsburgh has come away with a win five times in 11 chances when named as a favorite of at least -168 on the moneyline.
• The Pirates and their opponents have gone over in 73 of their 136 games with a total set by sportsbooks this season.
• The Pirates have an against the spread mark of 66-70-0 in 136 games with a line this season.
• The Giants have won 33 of the 90 games they were the underdog on the moneyline this season (36.7%).
• San Francisco has a 12-10 record (winning 54.5% of its games) when it has played as a moneyline underdog of +142 or longer.
• The Giants have had an over/under set by oddsmakers 135 times, and have combined with opponents to go over the total in 64 of those games (64-62-9).
• The Giants have a 64-71-0 record ATS this season (covering 47.4% of the time).

Pirates Player Leaders

• Bryan Reynolds leads Pittsburgh in OBP (.369) this season, fueled by 134 hits. He has a .262 batting average and a slugging percentage of .421.
• Among qualifying hitters, he ranks 58th in batting average, his on-base percentage ranks 18th, and he is 69th in slugging.
• Reynolds will look for his third straight game with a hit in this contest. During his last five outings he is batting .300 with a double and two walks.
• Brandon Lowe leads Pittsburgh in total hits (126) this season while batting .251 with 56 extra-base hits. He's slugging .476 with an on-base percentage of .320.
• Among qualified hitters, his batting average places him 80th, his on-base percentage 87th, and his slugging percentage 27th.
• Lowe brings a two-game streak with at least one hit into this matchup. In his last five games he is hitting .214 with a double, a home run, four walks and two RBIs.
• Nick Gonzales has hit six homers with a team-high .396 SLG this season.
• Gonzales takes a two-game hitting streak into this game. In his last five games he is batting .316 with a double, four walks and two RBIs.
• Oneil Cruz is batting .263 with a .351 OBP and 52 RBI for Pittsburgh this season.
• Cruz takes a three-game hitting streak into this game. During his last five outings he is hitting .316 with a double, a home run, three walks and an RBI.

Giants Player Leaders

• Rafael Devers has 131 hits, a team-high for the Giants. He's batting .252 and slugging .490 with an on-base percentage of .330.
• Including all qualified hitters, he is 78th in batting average, while his on-base percentage is 73rd and he is 22nd in slugging.
• Devers brings an eight-game hitting streak into this matchup. In his last 10 games he is hitting .342 with a double, four home runs, six walks and nine RBIs.
• Jung Hoo Lee paces his team with a .331 OBP, and has a club-high .419 slugging percentage. He has a batting average of .288.
• Including all qualifying hitters, his batting average places him 14th, his on-base percentage ranks 68th, and he is 72nd in slugging.
• Bryce Eldridge has 17 doubles, 15 home runs and 47 walks while batting .263.
• Drew Gilbert is batting .236 with 13 doubles, three triples, eight home runs and 33 walks.

Pirates vs Giants Head to Head

• 5/10/2026: 7-6 SF (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 5/9/2026: 13-3 PIT (Favorite: Pirates, Spread: -1.5, Total: 7, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 5/8/2026: 5-2 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 8/6/2025: 4-2 SF (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/5/2025: 8-1 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 8/4/2025: 5-4 PIT (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/30/2025: 2-1 PIT (Favorite: Giants, Spread: -1.5, Total: 7, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 7/29/2025: 3-1 PIT (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 7/28/2025: 6-5 PIT (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 5/23/2024: 7-6 SF (Favorite: Pirates, Spread: -1.5, Total: 8, Favorite Moneyline: -184, Underdog Moneyline: +154)

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