Penn State vs Wisconsin Prediction, Odds, Picks, Best Bets for Week 4 2026

Saturday's slate in college football includes a matchup between the Penn State Nittany Lions and the Wisconsin Badgers.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA football odds and spreads you need to know.

Penn State vs Wisconsin Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Penn State: (-400) | Wisconsin: (+310)
• Spread: Penn State: -9.5 (-120) | Wisconsin: +9.5 (-102)
• Total: 43.5 -- Over: (-115) | Under: (-105)

Penn State vs Wisconsin Betting Trends

• Penn State has won twice against the spread this year.
• Penn State has two wins ATS (2-1) as a 9.5-point or higher favorite in 2026.
• Penn State has had one game (of three) hit the over this season.
• Wisconsin has one win against the spread this season.
• Wisconsin has no wins ATS (0-1) as a 9.5-point underdog or more this year.
• Two Wisconsin games (of three) have gone over the point total this year.

Penn State vs Wisconsin Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Nittany Lions win (77.6%)

Penn State vs Wisconsin Point Spread

Penn State is a 9.5-point favorite against Wisconsin. Penn State is -120 to cover the spread, and Wisconsin is -102.

Penn State vs Wisconsin Over/Under

The Penn State-Wisconsin matchup on Sept. 26 has been given an over/under of 43.5 points. The over is -115 and the under is -105.

Penn State vs Wisconsin Moneyline

Looking at the moneyline for Penn State-Wisconsin, Penn State is the favorite at -400, and Wisconsin is +310.

Penn State vs. Wisconsin Points Insights

Penn State vs. Wisconsin Game Info

• Game day: Saturday, September 26, 2026
• Game time: 5 p.m. ET
• TV channel: Peacock
• Location: University Park, Pennsylvania
• Stadium: West Shore Home Field at Beaver Stadium

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Check out even more in-depth Penn State vs. Wisconsin analysis on FanDuel Research.