Padres vs Yankees Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 5

Odds updated as of 7:12 p.m.

On Saturday in MLB, the New York Yankees are up against the San Diego Padres.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Yankees vs Padres Game Info

• New York Yankees (80-61) vs. San Diego Padres (74-67)
• Date: Saturday, September 5, 2026
• Time: 7:15 p.m. ET
• Venue: Petco Park -- San Diego, California
• Coverage: FOX

Yankees vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYY: (-116) | SD: (-102)
• Spread: NYY: -1.5 (+150) | SD: +1.5 (-182)
• Total: 7.5 -- Over: (-104) | Under: (-118)

Yankees vs Padres Probable Starting Pitchers

Probable Pitchers: Carlos Rodon (Yankees) - 4-3, 3.20 ERA vs Robbie Ray (Padres) - 11-7, 3.14 ERA

The probable starters are Carlos Rodon (4-3) for the Yankees and Robbie Ray (11-7) for the Padres. When Rodon starts, his team is 5-7-0 against the spread this season. Rodon's team has won 66.7% of his starts when they are favored on the moneyline (6-3). The Padres have gone 15-9-0 ATS in Ray's 24 starts that had a set spread. The Padres are 5-7 in Ray's 12 starts this season that they were the moneyline underdog.

Yankees vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Yankees win (51.2%)

Yankees vs Padres Moneyline

• New York is a -116 favorite on the moneyline, while San Diego is a -102 underdog at home.

Yankees vs Padres Spread

• The Padres are hosting the Yankees, and are +1.5 on the runline. The Padres are +150 to cover the spread, and the Yankees are -182.

Yankees vs Padres Over/Under

• The over/under for Yankees-Padres on Sept. 5 is 7.5. The over is -104, and the under is -118.

Bet on New York Yankees vs. San Diego Padres on FanDuel today!

Yankees vs Padres Betting Trends

• The Yankees have been chosen as favorites in 109 games this year and have walked away with the win 64 times (58.7%) in those games.
• New York has a record of 60-43 in contests when bookmakers favor them by -116 or more on the moneyline.
• The Yankees and their opponents have gone over the total this season in 60 of their 136 opportunities.
• The Yankees are 68-68-0 against the spread in their 136 games with a line set by sportsbooks this season.
• The Padres have won 47.9% of the games this season they were the underdog on the moneyline (35-38).
• San Diego has gone 30-38 when playing as a moneyline underdog with odds of -102 or longer (44.1%).
• The Padres have had an over/under set by oddsmakers 141 times, and have combined with opponents to go over the total in 62 of those games (62-77-2).
• The Padres are 82-59-0 against the spread this season.

Yankees Player Leaders

• Ben Rice leads New York with an OBP of .349, plus a team-best slugging percentage of .526. He's batting .257 on the season.
• Among qualifying batters, he is 66th in batting average, his on-base percentage ranks 41st, and he is seventh in slugging.
• Rice will look for his fourth straight game with a hit in this contest. During his last five outings he is batting .348 with a home run and five RBIs.
• Luis Garcia has 130 hits to go with a slugging percentage of .545, both of which are best among New York hitters this season. He's batting .284 with an on-base percentage of .317.
• His batting average is 15th among qualified players, his on-base percentage 92nd, and his slugging percentage third.
• Cody Bellinger is batting .265 with a .416 slugging percentage and 60 RBI this year.
• Jazz Chisholm is batting .229 with a .310 OBP and 55 RBI for New York this season.

Padres Player Leaders

• Fernando Tatis Jr. has accumulated a team-high OBP (.348) and slugging percentage (.446), and paces the Padres in hits (154, while batting .282).
• Including all qualified hitters in the majors, he is 18th in batting average, 42nd in on-base percentage and 46th in slugging percentage.
• Manny Machado is hitting .220 with 21 doubles, 24 home runs and 66 walks. He's slugging .402 with an on-base percentage of .306.
• Including all qualifying players, he is 125th in batting average, 113th in on-base percentage and 89th in slugging percentage.
• Jackson Merrill is hitting .240 with 22 doubles, three triples, 22 home runs and 37 walks.
• Ty France is hitting .295 with 19 doubles, two triples, 20 home runs and 32 walks.

Yankees vs Padres Head to Head

• 9/4/2026: 3-2 SD (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/7/2025: 4-3 NYY (Favorite: Yankees, Spread: -1.5, Total: 8, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 5/6/2025: 12-3 NYY (Favorite: Yankees, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 5/5/2025: 4-3 SD (Favorite: Yankees, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/26/2024: 5-2 SD (Favorite: Yankees, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/25/2024: 4-1 NYY (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 5/24/2024: 8-0 NYY (Favorite: Yankees, Spread: -1.5, Total: 7, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 5/28/2023: 10-7 NYY (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/27/2023: 3-2 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 5/26/2023: 5-1 SD (Favorite: Padres, Spread: -1.5, Total: 9, Favorite Moneyline: -116, Underdog Moneyline: -102)

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