Padres vs Twins Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 23

Odds updated as of 3:12 p.m.

On Sunday in MLB, the San Diego Padres are up against the Minnesota Twins.

All the information you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Padres vs Twins Game Info

• San Diego Padres (70-60) vs. Minnesota Twins (63-67)
• Date: Sunday, August 23, 2026
• Time: 4:10 p.m. ET
• Venue: Petco Park -- San Diego, California
• Coverage: Padres.TV and Twins.TV

Padres vs Twins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-138) | MIN: (+128)
• Spread: SD: -1.5 (+140) | MIN: +1.5 (-170)
• Total: 8 -- Over: (-105) | Under: (-115)

Padres vs Twins Probable Starting Pitchers

Probable Pitchers: Walker Buehler (Padres) - 7-6, 4.79 ERA vs Bailey Ober (Twins) - 7-4, 4.62 ERA

The probable pitchers are Walker Buehler (7-6) for the Padres and Bailey Ober (7-4) for the Twins. Buehler's team is 18-7-0 against the spread this season in his starts. Buehler's team has won 66.7% of his starts when they are favored on the moneyline (6-3). The Twins have an 11-7-0 ATS record in Ober's 18 starts with a set spread. The Twins are 8-4 in Ober's 12 starts this season that they were the moneyline underdog.

Padres vs Twins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (58.5%)

Padres vs Twins Moneyline

• San Diego is the favorite, -138 on the moneyline, while Minnesota is a +128 underdog on the road.

Padres vs Twins Spread

• The Twins are at the Padres, and are +1.5 on the runline. The Twins are +140 to cover the spread, and the Padres are -170.

Padres vs Twins Over/Under

• The over/under for Padres-Twins on Aug. 23 is 8. The over is -105, and the under is -115.

Bet on San Diego Padres vs. Minnesota Twins on FanDuel today!

Padres vs Twins Betting Trends

• The Padres have been chosen as favorites in 56 games this year and have walked away with the win 32 times (57.1%) in those games.
• This season San Diego has been victorious 17 times in 25 chances when named as a favorite of at least -138 on the moneyline.
• The Padres and their opponents have gone over the total this season in 57 of their 130 opportunities.
• The Padres have posted a record of 75-55-0 against the spread this season.
• The Twins have won 36 of the 80 games they were the moneyline underdog this season (45%).
• Minnesota has a 12-14 record (winning 46.2% of its games) when playing as a moneyline underdog of +128 or longer.
• In the 127 games bookmakers have set an over/under for the Twins, they have combined with opponents to go over the total 70 times (70-54-3).
• The Twins have a 69-58-0 record ATS this season (covering 54.3% of the time).

Padres Player Leaders

• Fernando Tatis Jr. leads San Diego with 142 hits and an OBP of .357, plus a team-best slugging percentage of .438. He's batting .285.
• Among all qualified hitters in the majors, he ranks 19th in batting average, 35th in on-base percentage, and 56th in slugging.
• Tatis has recorded at least one hit in four games in a row. During his last five outings he is batting .400 with two doubles, two home runs, a walk and seven RBIs.
• Manny Machado has 20 doubles, 24 home runs and 60 walks. He's batting .216 and slugging .411 with an on-base percentage of .302.
• Among all qualified hitters, he is 128th in batting average, 114th in on-base percentage and 84th in slugging percentage.
• Jackson Merrill has 118 hits this season and has a slash line of .241/.292/.412.
• Xander Bogaerts has 11 home runs, 46 RBI and a batting average of .219 this season.

Twins Player Leaders

• Brooks Lee is hitting .247 with 20 doubles, three triples, 19 home runs and 33 walks. He's slugging .428 with an on-base percentage of .301.
• Including all qualified hitters in the big leagues, he is 86th in batting average, 115th in on-base percentage and 66th in slugging percentage.
• Josh Bell's .426 slugging percentage paces his team. He has a batting average of .254 with an on-base percentage of .320.
• He is currently 74th in batting average, 88th in on-base percentage and 67th in slugging percentage among all qualifying batters.
• Kody Clemens has 100 hits, a team-high for the Twins.
• Luke Keaschall paces his team with a .365 on-base percentage.

Padres vs Twins Head to Head

• 8/22/2026: 7-5 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -138, Underdog Moneyline: +128)
• 8/21/2026: 6-2 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: +108)
• 8/31/2025: 7-2 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 8/30/2025: 12-3 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/29/2025: 7-4 MIN (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 8/21/2024: 11-4 MIN (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 8/20/2024: 7-5 SD (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/19/2024: 5-3 SD (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 5/11/2023: 5-3 MIN (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 5/10/2023: 4-3 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)

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