Odds updated as of 6:11 PM

MLB action on Tuesday includes the San Diego Padres facing the Cincinnati Reds.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Padres vs Reds Game Info

• San Diego Padres (25-25) vs. Cincinnati Reds (19-28)
• Date: Tuesday, May 21, 2024
• Time: 6:40 PM ET
• Venue: Great American Ball Park -- Cincinnati, Ohio
• Coverage: SDPA

Padres vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-122) | CIN: (+104)
• Spread: SD: -1.5 (+128) | CIN: +1.5 (-154)
• Total: 9.5 -- Over: (-102) | Under: (-120)

Padres vs Reds Probable Starting Pitchers

Probable Pitchers: Joe Musgrove (Padres) - 3-3, 6.37 ERA vs Andrew Abbott (Reds) - 2-4, 3.06 ERA

The Padres will give the nod to Joe Musgrove (3-3, 6.37 ERA), who is eyeing win No. 4 on the season, and the Reds will turn to Andrew Abbott (2-4, 3.06 ERA). Musgrove's team is 4-4-0 against the spread this season in his starts. When Musgrove starts a game and his team is the favorite on the moneyline, they have a record of 3-2. The Reds have a 7-2-0 record against the spread in Abbott's starts. The Reds are 3-4 in Abbott's seven starts this season that they were the underdog on the moneyline.

Padres vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (62.6%)

Padres vs Reds Moneyline

• Looking at the moneyline for Padres-Reds, San Diego is the favorite at -122, and Cincinnati is +104 playing at home.

Padres vs Reds Spread

• The Reds are +1.5 on the run line against the Padres. The Reds are -154 to cover, and the Padres are +128.

Padres vs Reds Over/Under

• A combined run total of 9.5 has been set for Padres-Reds on May 21, with the over at -102 and the under at -120.

Bet on San Diego Padres vs. Cincinnati Reds on FanDuel today!

Padres vs Reds Betting Trends

• The Padres have won in 13, or 46.4%, of the 28 contests they have been named as odds-on favorites in this year.
• San Diego has a record of 9-11 in contests when sportsbooks favor them by -122 or more on the moneyline.
• The Padres and their opponents have gone over in 25 of their 49 games with a total set by sportsbooks this season.
• The Padres are 23-26-0 against the spread in their 49 games with a line set by sportsbooks this season.
• The Reds have been the underdog on the moneyline 26 total times this season. They've finished 7-19 in those games.
• Cincinnati has a record of 5-15 when it has played as a moneyline underdog with odds of +104 or longer (25%).
• In the 45 games bookmakers have set an over/under for the Reds, they have combined with opponents to go over the total 22 times (22-21-2).
• The Reds have a 24-21-0 record ATS this season.

Padres Player Leaders

• Jurickson Profar leads San Diego with 57 hits and an OBP of .426 this season. He has a .339 batting average and a slugging percentage of .518.
• Among qualifying hitters in baseball, his batting average ranks third, his on-base percentage ranks second, and he is 16th in slugging.
• Profar hopes to build on a nine-game hitting streak in this matchup. During his last 10 outings he is batting .382 with a double, a home run, seven walks and four RBI.
• Jake Cronenworth has 10 doubles, a triple, eight home runs and 18 walks. He's batting .270 and slugging .472 with an on-base percentage of .340.
• He is 45th in batting average, 49th in on-base percentage and 38th in slugging in the majors.
• Fernando Tatis Jr. has collected 48 base hits, an OBP of .336 and a slugging percentage of .420 this season.
• Ha-Seong Kim has been key for San Diego with 37 hits, an OBP of .332 plus a slugging percentage of .368.
• Kim takes a four-game hitting streak into this matchup. In his last five games he is hitting .294 with a home run, three walks and an RBI.

Reds Player Leaders

• Elly De La Cruz has put up an on-base percentage of .352, a slugging percentage of .476, and has 43 hits, all club-highs for the Reds (while batting .256).
• Including all the qualifying hitters in the big leagues, he is 67th in batting average, 34th in on-base percentage and 33rd in slugging percentage.
• Spencer Steer is hitting .224 with 10 doubles, a triple, four home runs and 24 walks. He's slugging .373 with an on-base percentage of .337.
• Including all qualifying hitters, he is 117th in batting average, 55th in on-base percentage and 107th in slugging percentage.
• Tyler Stephenson is hitting .273 with seven doubles, five home runs and 13 walks.
• Jonathan India is hitting .219 with three doubles, a triple, two home runs and 22 walks.

Padres vs Reds Head to Head

• 5/1/2024: 6-2 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 4/30/2024: 6-4 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 4/29/2024: 5-2 CIN (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 7/2/2023: 4-3 CIN (Favorite: Reds, Spread: -1.5, Total: 11, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/1/2023: 12-5 SD (Favorite: Padres, Spread: -1.5, Total: 11.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 6/30/2023: 7-5 CIN (Favorite: Padres, Spread: -1.5, Total: 10.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 4/28/2022: 7-5 SD (Favorite: Reds, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/27/2022: 8-5 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 4/26/2022: 9-6 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 4/20/2022: 6-0 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -196, Underdog Moneyline: +164)

Join FanDuel Sportsbook today with $150 in Bonus Bets - win or lose - when you place your first $5 bet!