Padres vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 8

Odds updated as of 4:12 a.m.

The MLB's Tuesday schedule includes the San Diego Padres taking on the Washington Nationals.

We've got you covered, in terms of the most important information about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Padres vs Nationals Game Info

• San Diego Padres (76-68) vs. Washington Nationals (67-79)
• Date: Tuesday, September 8, 2026
• Time: 9:40 p.m. ET
• Venue: Petco Park -- San Diego, California
• Coverage: Padres.TV and Nationals.TV

Padres vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-188) | WSH: (+158)
• Spread: SD: -1.5 (+126) | WSH: +1.5 (-152)
• Total: 7.5 -- Over: (-120) | Under: (-102)

Padres vs Nationals Probable Starting Pitchers

Probable Pitchers: Casey Mize (Padres) - 5-9, 3.64 ERA vs Riley Cornelio (Nationals) - 2-2, 5.96 ERA

This contest's pitching matchup is set, as the Padres will send Casey Mize (5-9) to the mound, while Riley Cornelio (2-2) will take the ball for the Nationals. Mize and his team are 11-11-0 ATS this season when he starts. Mize's team has won 50% of his starts when they are favored on the moneyline (6-6). Cornelio's team was never a moneyline underdog a season ago in games he pitched.

Padres vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (58.1%)

Padres vs Nationals Moneyline

• San Diego is a -188 favorite on the moneyline, while Washington is a +158 underdog on the road.

Padres vs Nationals Spread

• The Nationals are +1.5 on the run line against the Padres. The Nationals are -152 to cover, and the Padres are +126.

Padres vs Nationals Over/Under

• The over/under for the Padres versus Nationals contest on Sept. 8 has been set at 7.5, with -120 odds on the over and -102 odds on the under.

Bet on San Diego Padres vs. Washington Nationals on FanDuel today!

Padres vs Nationals Betting Trends

• The Padres have come away with 37 wins in the 66 contests they have been listed as the favorites in this season.
• This season San Diego has come away with a win four times in five chances when named as a favorite of at least -188 on the moneyline.
• Contests with the Padres have gone over the total set by oddsmakers in 62 of 144 chances this season.
• The Padres are 83-61-0 against the spread in their 144 games with a line set by sportsbooks this season.
• The Nationals have won 48 of the 111 games they were the moneyline underdog this season (43.2%).
• Washington has a 7-15 record (winning just 31.8% of its games) when it has played as a moneyline underdog of +158 or longer.
• The Nationals have played in 142 games with an over/under set, and have combined with opponents to go over the total 73 times (73-63-6).
• The Nationals have covered 55.6% of their games this season, going 79-63-0 against the spread.

Padres Player Leaders

• Fernando Tatis Jr. leads San Diego in OBP (.349), slugging percentage (.450) and total hits (158) this season. He has a .283 batting average.
• Among all qualifying hitters in baseball, he ranks 16th in batting average, 44th in on-base percentage, and 47th in slugging.
• Tatis hopes to build on a two-game hitting streak in this matchup. During his last five outings he is batting .316 with a home run, a walk and two RBIs.
• Manny Machado is hitting .224 with 22 doubles, 26 home runs and 69 walks. He's slugging .416 with an on-base percentage of .312.
• He is 120th in batting average, 101st in on-base percentage and 76th in slugging in the major leagues.
• Machado brings a four-game streak with at least one hit into this one. In his last five games he is batting .333 with a double, two home runs, four walks and four RBIs.
• Jackson Merrill is batting .241 with a .415 slugging percentage and 72 RBI this year.
• Ty France is batting .288 with a .359 OBP and 62 RBI for San Diego this season.

Nationals Player Leaders

• James Wood has racked up a team-best OBP (.394), while pacing the Nationals in hits (122). He's batting .268 and slugging.
• Including all the qualifying hitters in the majors, he ranks 46th in batting average, third in on-base percentage and fourth in slugging percentage.
• Wood takes a six-game hitting streak into this game. During his last 10 games he is batting .222 with three doubles, eight walks and two RBIs.
• C.J. Abrams is hitting .262 with 26 doubles, three triples, 30 home runs and 52 walks. He's slugging .496 with an on-base percentage of .340.
• His batting average ranks 60th among all qualified players, his on-base percentage is 52nd, and he is 15th in slugging.
• Daylen Lile has a .440 slugging percentage, which paces the Nationals.
• Jacob Young is batting .249 with 19 doubles, three triples, 10 home runs and 32 walks.

Padres vs Nationals Head to Head

• 9/7/2026: 3-2 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 5/31/2026: 4-2 WSH (Favorite: Padres, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/30/2026: 9-4 WSH (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/29/2026: 7-5 SD (Favorite: Nationals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/20/2025: 8-1 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 7/18/2025: 7-2 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 6/25/2025: 1-0 SD (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 6/24/2025: 4-3 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 6/23/2025: 10-6 WSH (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 7/25/2024: 3-0 SD (Favorite: Padres, Spread: -1.5, Total: 9, Favorite Moneyline: -162, Underdog Moneyline: +136)

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