Padres vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 8

Odds updated as of 9:12 p.m.

On Tuesday in MLB, the San Diego Padres are playing the Washington Nationals.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital info about this game.

Padres vs Nationals Game Info

• San Diego Padres (76-68) vs. Washington Nationals (67-79)
• Date: Tuesday, September 8, 2026
• Time: 9:40 p.m. ET
• Venue: Petco Park -- San Diego, California
• Coverage: Padres.TV and Nationals.TV

Padres vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-190) | WSH: (+160)
• Spread: SD: -1.5 (+114) | WSH: +1.5 (-137)
• Total: 8.5 -- Over: (+108) | Under: (-132)

Padres vs Nationals Probable Starting Pitchers

Probable Pitchers: Casey Mize (Padres) - 5-9, 3.64 ERA vs Riley Cornelio (Nationals) - 2-2, 5.96 ERA

The Padres will call on Casey Mize (5-9) versus the Nationals and Riley Cornelio (2-2). Mize's team is 11-11-0 against the spread this season in his starts. Mize's team has been victorious in 50% of the games he's started as the moneyline favorite with a record of 6-6. Cornelio never pitched as a moneyline underdog a season ago.

Padres vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (55%)

Padres vs Nationals Moneyline

• San Diego is the favorite, -190 on the moneyline, while Washington is a +160 underdog on the road.

Padres vs Nationals Spread

• The Nationals are +1.5 on the run line against the Padres. The Nationals are -137 to cover, and the Padres are +114.

Padres vs Nationals Over/Under

• The over/under for Padres-Nationals on Sept. 8 is 8.5. The over is +108, and the under is -132.

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Padres vs Nationals Betting Trends

• The Padres have won in 37, or 56.1%, of the 66 contests they have been named as odds-on favorites in this year.
• San Diego has a record of 4-1 when favored by -190 or more this year.
• The Padres and their opponents have gone over in 62 of their 144 games with a total set by sportsbooks this season.
• The Padres have an against the spread record of 83-61-0 in 144 games with a line this season.
• The Nationals have gone 48-63 in games they were listed as the moneyline underdog (winning 43.2% of those games).
• Washington is 6-14 (winning just 30% of its games) when playing as a moneyline underdog of +160 or longer.
• In the 142 games bookmakers have set an over/under for the Nationals, they have combined with opponents to go over the total 73 times (73-63-6).
• The Nationals have gone 79-63-0 ATS this season.

Padres Player Leaders

• Fernando Tatis Jr. leads San Diego in OBP (.349), slugging percentage (.450) and total hits (158) this season. He has a .283 batting average.
• Among qualified hitters in MLB, his batting average ranks 16th, his on-base percentage ranks 44th, and he is 47th in slugging.
• Tatis hopes to build on a two-game hitting streak in this matchup. In his last five games he is hitting .316 with a home run, a walk and two RBIs.
• Manny Machado is hitting .224 with 22 doubles, 26 home runs and 69 walks. He's slugging .416 with an on-base percentage of .312.
• His batting average ranks 120th among qualified players, his on-base percentage 101st, and his slugging percentage 76th.
• Machado heads into this game looking to extend his four-game hit streak. In his last five games he is hitting .333 with a double, two home runs, four walks and four RBIs.
• Jackson Merrill is batting .241 with a .415 slugging percentage and 72 RBI this year.
• Ty France is batting .288 with a .359 OBP and 62 RBI for San Diego this season.

Nationals Player Leaders

• James Wood has put up an on-base percentage of .394 and has 122 hits, both team-high marks for the Nationals. He's batting .268 and slugging .533.
• Including all qualified players in the big leagues, he is 46th in batting average, third in on-base percentage and fourth in slugging percentage.
• Wood takes a six-game hitting streak into this game. In his last 10 games he is hitting .222 with three doubles, eight walks and two RBIs.
• C.J. Abrams is batting .262 with 26 doubles, three triples, 30 home runs and 52 walks. He's slugging .496 with an on-base percentage of .340.
• He is currently 60th in batting average, 52nd in on-base percentage and 15th in slugging percentage among all qualifying hitters.
• Daylen Lile has a .440 slugging percentage, which leads the Nationals.
• Jacob Young is hitting .249 with 19 doubles, three triples, 10 home runs and 32 walks.

Padres vs Nationals Head to Head

• 9/7/2026: 3-2 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 5/31/2026: 4-2 WSH (Favorite: Padres, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/30/2026: 9-4 WSH (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/29/2026: 7-5 SD (Favorite: Nationals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/20/2025: 8-1 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 7/18/2025: 7-2 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 6/25/2025: 1-0 SD (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 6/24/2025: 4-3 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 6/23/2025: 10-6 WSH (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 7/25/2024: 3-0 SD (Favorite: Padres, Spread: -1.5, Total: 9, Favorite Moneyline: -162, Underdog Moneyline: +136)

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